High infliximab trough concentrations are associated with sustained histologic remission in inflammatory bowel disease: a prospective cohort study

Table 3 Association between sustained histologic remission and covariates

Covariate	Odds ratio	95% CI	p-value
Age (years)	0.997	0.963–1.034	0.89
Weight (kg)	0.991	0.966–1.016	0.47
Sex	0.649	0.243–1.735	0.39
Diagnosis (CD or UC)	1.038	0.343–3.143	0.95
Methotrexate co-exposure	0.256	0.086–0.756	0.014
Azathioprine co-exposure	1.050	0.328–3.367	0.93
Presence of anti-infliximab antibodies	0.00	0.000	0.999
Disease duration (years)	0.934	0.854–1.022	0.14
Concentration > 8.27 μg/ml	3.045	1.135–8.169	0.027

ISSN: 1471-230X