Table 1 Association of variables with screening colonoscopy outcomes
From: Polygenic risk score is a predictor of adenomatous polyps at screening colonoscopy
Univariate analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
Variables | Positive1 (N = 520) | Negative2 (N = 1249) | OR (95% CI) | p | OR (95% CI) | p |
Age at colonoscopy, mean (95% CI) | 61.0 (60.3–61.6) | 60.2 (59.8–60.6) | 1.01 (1–1.03) | 0.04 | 1.01 (1–1.02) | 0.1 |
Gender, No. (%) of male | 247 (47.5) | 411 (32.9) | 1.84 (1.55–2.2) | < 0.001 | 1.8 (1.51–2.15) | < 0.001 |
Positive family history, No. (%) | 40 (7.7) | 87 (7.0) | 1.11 (0.8–1.54) | 0.66 | 1.14 (0.81–1.58) | 0.53 |
BMI, mean (95% CI) | 29.5 (28.9–30) | 28.0 (27.7–28.3) | 1.04 (1.02–1.05) | < 0.001 | 1.04 (1.02–1.05) | < 0.001 |
GRS, mean (95% CI) | 1.02 (1–1.05) | 0.97 (0.95–0.99) | 1.61 (1.24–2.08) | < 0.001 | 1.63 (1.25–2.12) | < 0.001 |