Table 1 Demographic and disease characteristics of patients diagnosed between June 2003 and December 2009 (Group 1) and January 2010–June 2016 (Group 2)
Characteristic | Group 1 (n = 100) | Group 2 (n = 275) | p value |
|---|---|---|---|
Overall (n = 375) |  |  |  |
Male gender | 50 (50.0) | 138 (51.2) | 0.83 |
Age at diagnosis (mean, SD) | 46.0 (14.5) | 43.6 (16.6) | 0.19 |
Ulcerative colitis | 77 (77.0) | 150 (54.5) |  < 0.01 |
Crohn's disease | 23 (23.0) | 125 (45.5) |  < 0.01 |
Ulcerative colitis (n = 227) |  |  |  |
Complicated disease (CompD) | 29 (36.2) | 40 (32.0) | 0.14 |
Treatment refractory disease (TRD) | 4 (5.2) | 17 (13.6) | 0.05 |
Disease extent—proctitis | 11 (14.3) | 29 (19.3) | 0.35 |
Disease extent—left sided colitis | 38 (49.4) | 87 (58.0) | 0.22 |
Disease extent—extensive colitis | 28 (36.4) | 34 (22.7) | 0.02 |
Crohn’s disease (n = 148) |  |  |  |
Complicated disease (CompD) | 14 (60.8) | 34 (27.6) | 0.07 |
Treatment refractory disease (TRD) | 4 (17.4) | 20 (16.4) | 0.91 |
Disease extent—confined to ileum | 4 (17.4) | 29 (24.6) | 0.46 |
Disease extent—confined to colon | 3 (13.0) | 32 (27.1) | 0.15 |
Disease extent—ileocolonic disease | 15 (65.2) | 57 (48.3) | 0.14 |
Perianal disease | 7 (30.4) | 28 (22.8) | 0.43 |
Disease behaviour—inflammatory | 16 (69.5) | 105 (84.0) | 0.10 |
Disease behaviour—stricturing | 6 (26.1) | 5 (4.0) |  < 0.01 |
Disease behaviour—fistulating | 1 (4.3) | 15 (12.0) | 0.28 |