Table 1 Patients’ characteristics. Numeric data are expressed as median (IQR: interquartile range). Categorical data are shown as number (%). BMI: Body mass index; PPIs: proton pump inhibitors; Obesity was considered when the BMI was 30.0 or higher
Overall cohort n = 38 | Negative-SeHCAT group n = 18 | Positive-SeHCAT group n = 20 | p-value | |
|---|---|---|---|---|
Age, years | 37.5 (27.2–50.2) | 37.0 (23.7–51.7) | 39.0 (29.5–49.2) | 0.640 |
Sex, male, % | 20 (52.6) | 8 (44.4) | 12 (60.0) | 0.338 |
Obesity | 10 (32.3) | 3 (20) | 7 (43.8) | 0.252 |
BMI, kg/m2 | 25.1 (21.1–30) | 22 (18.7–26.6) | 27.8 (23.6–35.3) | 0.006 |
Concomitant medications, % | 27 (71.1) | 12 (66.7) | 15 (75.0) | 0.572 |
Antihypertensives | 5 (13.2) | 1 (5.6) | 4 (20.0) | 0.344 |
PPIs | 12 (31.6) | 7 (38.9) | 5 (25.0) | 0.358 |
Statins | 3 (7.9) | 3 (16.7) | 0 (0) | 0.097 |
Spasmolytics | 6 (15.8) | 4 (22.2) | 2 (10.0) | 0.395 |
Probiotics | 2 (5.3) | 0 (0) | 2 (10.0) | 0.488 |
Rifaximin | 7 (18.4) | 5 (27.8) | 2 (10.0) | 0.222 |
Benzodiazepines | 2 (5.3) | 0 (0) | 2 (10.0) | 0.488 |
Antidepressants | 3 (7.9) | 0 (0) | 3 (15.0) | 0.232 |
Anticonvulsants | 3 (7.9) | 1 (5.6) | 2 (10.0) | 1.000 |
Immunosuppressants | 2 (5.3) | 1 (5.6) | 1 (5.0) | 1.000 |
SeHCAT result, % of retention | 9.73 (2.9–28.7) | 29.1 (21.2–34.1) | 3.5 (0.3–6.6) | 0.000 |
Symptoms duration before SeHCAT, months | 20.8 (12.5 – 46.6) | 29.5 (12.6–56.2) | 15.3 (12.3–32.3) | 0.270 |
Daily number of bowel movements | 5 (4–6) | 6 (4–6) | 5 (4–7) | 0.765 |
Abdominal pain, % | 17 (48.6) | 10 (55.6) | 7 (41.2) | 0.395 |
Faecal urgency, % | 11 (28.9) | 6 (40.0) | 5 (29.4) | 0.529 |