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Table 1 Patients’ characteristics. Numeric data are expressed as median (IQR: interquartile range). Categorical data are shown as number (%). BMI: Body mass index; PPIs: proton pump inhibitors; Obesity was considered when the BMI was 30.0 or higher

From: Prevalence of biliary acid malabsorption in patients with chronic diarrhoea of functional characteristics: a prospective study

  Overall cohort
n = 38
Negative-SeHCAT group
n = 18
Positive-SeHCAT group
n = 20
p-value
Age, years 37.5 (27.2–50.2) 37.0 (23.7–51.7) 39.0 (29.5–49.2) 0.640
Sex, male, % 20 (52.6) 8 (44.4) 12 (60.0) 0.338
Obesity 10 (32.3) 3 (20) 7 (43.8) 0.252
BMI, kg/m2 25.1 (21.1–30) 22 (18.7–26.6) 27.8 (23.6–35.3) 0.006
Concomitant medications, % 27 (71.1) 12 (66.7) 15 (75.0) 0.572
 Antihypertensives 5 (13.2) 1 (5.6) 4 (20.0) 0.344
 PPIs 12 (31.6) 7 (38.9) 5 (25.0) 0.358
 Statins 3 (7.9) 3 (16.7) 0 (0) 0.097
 Spasmolytics 6 (15.8) 4 (22.2) 2 (10.0) 0.395
 Probiotics 2 (5.3) 0 (0) 2 (10.0) 0.488
 Rifaximin 7 (18.4) 5 (27.8) 2 (10.0) 0.222
 Benzodiazepines 2 (5.3) 0 (0) 2 (10.0) 0.488
 Antidepressants 3 (7.9) 0 (0) 3 (15.0) 0.232
 Anticonvulsants 3 (7.9) 1 (5.6) 2 (10.0) 1.000
 Immunosuppressants 2 (5.3) 1 (5.6) 1 (5.0) 1.000
SeHCAT result, % of retention 9.73 (2.9–28.7) 29.1 (21.2–34.1) 3.5 (0.3–6.6) 0.000
Symptoms duration before SeHCAT, months 20.8 (12.5 – 46.6) 29.5 (12.6–56.2) 15.3 (12.3–32.3) 0.270
Daily number of bowel movements 5 (4–6) 6 (4–6) 5 (4–7) 0.765
Abdominal pain, % 17 (48.6) 10 (55.6) 7 (41.2) 0.395
Faecal urgency, % 11 (28.9) 6 (40.0) 5 (29.4) 0.529
  1. Bold values indicate statistically significant p < 0.05