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Table 3 Univariable and multivariable Cox proportional hazard regression analyses of the characteristics in training cohort

From: A prognostic model for stratification of stage IB/IIA esophageal squamous cell carcinoma: a retrospective study

Variables

Univariable analysis

Multivariable analysis

HR

95% CI

P value

HR

95% CI

P value

Sex

      

 Male

1 (reference)

    

 Female

1.170

0.665–2.061

0.586

   

Age (year, continuous)

1.024

0.995–1.053

0.107

   

Smoking status

      

 No

1 (reference)

    

 Yes

1.305

0.764–2.231

0.330

   

Drinking status

      

 No

1 (reference)

    

 Yes

1.627

0.949–2.790

0.077

   

Differentiation

      

 Well-moderate

1 (reference)

    

 Poor

0.681

0.406–1.140

0.144

   

pT stage

      

 T2

1 (reference)

    

 T3

1.677

0.952–2.954

0.073

   

pTNM stage

      

 IB

1 (reference)

 

1 (reference)

 

 IIA

2.080

1.101–3.930

0.024

1.987

1.050–3.761

0.035

Tumor length (cm, continuous)

1.031

0.889–1.197

0.684

   

Surgery approach

      

 Left

1 (reference)

    

 Right

0.624

0.330–1.179

0.146

   

NLNs (continuous)

0.960

0.935–0.985

0.002

0.963

0.938–0.989

0.006

PD-L1 expression

      

 Low

1 (reference)

 

1 (reference)

 

 High

4.910

2.770–8.702

< 0.001

4.746

2.669–8.438

< 0.001

Dissection of left gastric artery LNs

      

 No

1 (reference)

    

 Yes

4.338

0.599–31.44

0.146

   

Dissection of subcarinal LNs

      

 No

1 (reference)

    

 Yes

0.965

0.349–2.668

0.946

   

LNs dissection of left recurrent laryngeal nerve

      

 No

1 (reference)

    

 Yes

1.362

0.756–2.452

0.304

   

LNs dissection of right recurrent laryngeal nerve

      

 No

1 (reference)

    

 Yes

1.128

0.634–2.008

0.681

   
  1. Multivariable analysis’s method is Forward: LR
  2. HR, hazard ratio; CI, confidential interval; NLNs, the number of lymph nodes; LNs, lymph nodes