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Table 3 Comparison of the concentrations of biochemical parameters among healthy volunteers, patients with PC and benign pancreatic diseases

From: Evaluation of serum ATX and LPA as potential diagnostic biomarkers in patients with pancreatic cancer

Biomarkers

HVs

BPDs

PCs

p value (s)

(n = 120)

(n = 94)

Total (n = 114)

TS1 + TS2

(n = 45)

TS3 + TS4

(n = 69)

PC vs. HVs

PC vs. BPDs

TS1 + TS2 vs. HVs

TS1 + TS2 vs. BPDs

TS1 + TS2 vs. TS3 + TS4

ATX (ng/mL)

          

 Median

255.3

267.5

392.6

294.9

422

< 0.001

< 0.001

0.005*

0.023*

< 0.001

 Range

130–1408

184–977

297–1753

262–1455

312–1620

     

LPA(ug/mL)

          

 Median

10.8

9.83

17.48

15.75

24.6

0.004*

< 0.001

0.057

0.044*

0.002*

 Range

5.2–49

4.9–28.2

8.1–97

8.3–92

9.5–97.3

     

CA19-9 (U/mL)

          

 Median

36.3

51.2

185.4

131.1

217.4

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

 Range

13–69.1

21–105.3

24–970

23–289

32–970

     
  1. HVs, healthy volunteers; PC, pancreatic cancer; TS, tumor stage
  2. *Depicts significance at p value < 0.05