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Table 1 Blood ANGP-2 measurement profiles of the study participants. The results are provided as means ± SDs

From: Blood angiopoietin-2 predicts liver angiogenesis and fibrosis in hepatitis C patients

 

Healthy volunteers (HVs)

Hepatitis C virus ( +) (HCV) patients

Number

15

20

Age (median, range)

26 (21–47)

70 (38–84)

Gender (M/F)

2/13

11/9

Glecaprevir + Pibrentasvir

–

14

Ledipasvir + Sofosbuvir

–

5

Elbasvir + Grazopervir

–

1

ANGP-2 (pg/mL)

1896 ± 771.7

3115 ± 1116

M2BPGi (c. o. i.)

N. A

3.56 ± 3.25

VTQ (m/s)

N. A

1.74 ± 0.80

PLT (× 104/μL)

N. A

14.9 ± 5.7

ALBI score

N. A

– 2.667 ± 0.3693

PT (INR)

N. A

1.04 ± 0.09

Albumin

N. A

4 ± 0.4

ALT (IU/L)

N. A

48.80 ± 37.65

AFP (ng/mL)

N. A

15.4 ± 34.2

DCP (mAU/mL)

N. A

20.2 ± 9.5

Pathological examination

N. A

14

Metavir F-stage

F0/F1/F2/F3/F4

 

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  1. ANGP-2; angiopoietin-2; VTQ, virtual touch quantification; PLT, platelet; ALBI score, albumin bilirubin score; PT, prothrombin time; ALT, alanine transaminase; AFP, alpha-fetoprotein; DCP, des-γ-carboxy prothrombin