Fig. 3
From: Identification of potential biomarkers for abdominal pain in IBS patients by bioinformatics approach
The Molecular Complex Detection (MCODE) components of the protein–protein interaction (PPI) network identified gens associated with pain transmission. Several outstanding hub genes such as CCKBR, NPFF, GRPR, BDKRB2, CXCR1 and CCL13 (red rectangle) was clustered. Degree > 10 was set as the cut-off criterion. Rectangle represent DEGs and lines represent interaction and relationship between nodes