Skip to main content

Table 2 Analysed single-nucleotide polymorphisms

From: Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management

Name

A1A2a

Associated gene

Chromosome

Reference

rs1062613

CT

5-HT3A (5-hydroxytryptamine receptor 3E)

11

[20]

rs12702514

CT

KDELR2 (ER lumen protein retaining receptor 2)

7

[16]

rs1800795

GC

Il6 (Interleukin 6)

7

[19, 20]

rs324420

CA

FAAH (Fatty acid amide hydrolase)

1

[20]

rs4663866

AC

HES6 (Hes family bHLH transcription factor 6)

2

[16]

rs1042173

AC

SLC64A (Solute carrier family 6)

17

[20]

rs1042713

GA

ADRB2 (Beta-2-adrenergic receptor)

5

[20]

rs110402

GA

CRHR1 (Corticotropin-releasing hormone receptor 1)

17

[20]

rs2020936

AG

SLC64A (Solute carrier family 6)

17

[20]

rs242924

TG

CRHR1 (Corticotropin-releasing hormone receptor 1)

17

[20]

rs3779250

CT

CRHR1 (Corticotropin-releasing hormone receptor 2)

7

[20]

rs4680

GA

COMT (Catechol-O-methyltransferase)

22

[20]

rs6269

AG

COMT (Catechol-O-methyltransferase)

22

[20]

rs6311

CT

HTR2A (5-hydroxytryptamine receptor 2A)

13

[20]

rs7432532

AC

SCN5A (sodium voltage-gated channel alpha subunit 5)

3

[16]

rs2243250

CT

IL4 (Interleukin 4)

5

[16, 19, 20]

  1. aA1: major allele, A2: minor allele