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Table 2 Multivariate analysis for exploring potential risk factors for prognosis of AEG

From: Development and validation of a novel competing risk model for predicting survival of esophagogastric junction adenocarcinoma: a SEER population-based study and external validation

Characteristics Initial multivariate model Final multivariate model
SHR (95% CI) P beta SHR (95% CI) P
Age (year)
 < 60 Reference    Reference  
 ≥ 60 1.393 (1.223–1.588)  < 0.001 0.329 1.389 (1.220–1.583)  < 0.001
T stage
 T1 Reference    Reference  
 T2 1.604 (1.204 -2.137) < 0.001 0.465 1.592 (1.211–2.093) < 0.001
 T3 2.207 (1.698–2.869) < 0.001 0.773 2.167 (1.710–2.747) < 0.001
 T4 2.606 (1.990–3.411) < 0.001 0.938 2.555 (2.000–3.265) < 0.001
N stage
 N0 Reference    Reference  
 N1 1.831 (1.525–2.198) < 0.001 0.596 1.814 (1.515–2.172) < 0.001
 N2 2.536 (2.089–3.077) < 0.001 0.918 2.505 (2.073–3.028) < 0.001
 N3 3.417 (2.750–4.247) < 0.001 1.205 3.335 (2.702–4.116) < 0.001
Grade
 Low grade Reference    Reference  
 High grade 1.277 (1.120–1.457) < 0.001 0.248 1.281 (1.124–1.460) < 0.001
Number of examined lymph nodes
 < 5 Reference    Reference  
 < 10 0.736 (0.555–0.975) 0.032 − 0.286 0.751 (0.569–0.993) 0.040
 < 15 0.630 (0.477–0.832) 0.001 − 0.455 0.635 (0.481–0.838) 0.013
 ≥ 15 0.535 (0.410–0.698) < 0.001 − 0.616 0.540 (0.414–0.704) < 0.001
Race
 White Reference     
 Black 0.973 (0.713–1.329) 0.860    
 Others 0.829 (0.662–1.039) 0.100    
Sex
 Female Reference     
 Male 0.965 (0.825–1.129) 0.660    
Size (cm)
 < 1.0 Reference     
 < 2.0 1.179 (0.732–1.899) 0.500    
 < 3.0 1.087 (0.682–1.731) 0.730    
 < 5.0 1.121 (0.707–1.777) 0.630    
 ≥ 5.0 1.048 (0.659–1.668) 0.840    
  1. SHR sub-distribution hazard ratio, CI confidential interval