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Table 2 Multivariate analysis for exploring potential risk factors for prognosis of AEG

From: Development and validation of a novel competing risk model for predicting survival of esophagogastric junction adenocarcinoma: a SEER population-based study and external validation

Characteristics

Initial multivariate model

Final multivariate model

SHR (95% CI)

P

beta

SHR (95% CI)

P

Age (year)

 < 60

Reference

  

Reference

 

 ≥ 60

1.393 (1.223–1.588)

 < 0.001

0.329

1.389 (1.220–1.583)

 < 0.001

T stage

 T1

Reference

  

Reference

 

 T2

1.604 (1.204 -2.137)

< 0.001

0.465

1.592 (1.211–2.093)

< 0.001

 T3

2.207 (1.698–2.869)

< 0.001

0.773

2.167 (1.710–2.747)

< 0.001

 T4

2.606 (1.990–3.411)

< 0.001

0.938

2.555 (2.000–3.265)

< 0.001

N stage

 N0

Reference

  

Reference

 

 N1

1.831 (1.525–2.198)

< 0.001

0.596

1.814 (1.515–2.172)

< 0.001

 N2

2.536 (2.089–3.077)

< 0.001

0.918

2.505 (2.073–3.028)

< 0.001

 N3

3.417 (2.750–4.247)

< 0.001

1.205

3.335 (2.702–4.116)

< 0.001

Grade

 Low grade

Reference

  

Reference

 

 High grade

1.277 (1.120–1.457)

< 0.001

0.248

1.281 (1.124–1.460)

< 0.001

Number of examined lymph nodes

 < 5

Reference

  

Reference

 

 < 10

0.736 (0.555–0.975)

0.032

− 0.286

0.751 (0.569–0.993)

0.040

 < 15

0.630 (0.477–0.832)

0.001

− 0.455

0.635 (0.481–0.838)

0.013

 ≥ 15

0.535 (0.410–0.698)

< 0.001

− 0.616

0.540 (0.414–0.704)

< 0.001

Race

 White

Reference

    

 Black

0.973 (0.713–1.329)

0.860

   

 Others

0.829 (0.662–1.039)

0.100

   

Sex

 Female

Reference

    

 Male

0.965 (0.825–1.129)

0.660

   

Size (cm)

 < 1.0

Reference

    

 < 2.0

1.179 (0.732–1.899)

0.500

   

 < 3.0

1.087 (0.682–1.731)

0.730

   

 < 5.0

1.121 (0.707–1.777)

0.630

   

 ≥ 5.0

1.048 (0.659–1.668)

0.840

   
  1. SHR sub-distribution hazard ratio, CI confidential interval
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BMC Gastroenterology

ISSN: 1471-230X

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