From: Obesity interacts with hyperuricemia on the severity of non-alcoholic fatty liver disease
 | All NAFLD | Normo-uricemia | Hyper-uricemia | P value |
---|---|---|---|---|
Numbers, n | 557 | 424 | 133 | Â |
Age (years)* | 50.77 ± 13.66 | 52.09 ± 12.49 | 46.54 ± 16.20 | < 0.001 |
Gender(male), n% | 344 (61.8%) | 265 (62.5%) | 79 (59.4%) | 0.521 |
BMI (kg/m2)* | 26.99 ± 3.18 | 26.83 ± 3.04 | 27.51 ± 3.52 | 0.03 |
TG (mmol/L)* | 2.37 ± 1.71 | 2.24 ± 1.60 | 2.76 ± 1.98 | 0.006 |
HDL-C (mmol/L) | 1.06 ± 0.28 | 1.06 ± 0.28 | 1.07 ± 0.29 | 0.686 |
FPG (mmol/L) | 7.04 ± 3.05 | 7.09 ± 3.03 | 6.88 ± 3.12 | 0.487 |
Obesity, n (%) | 411 (73.8%) | 306 (72.2%) | 105 (78.9%) | 0.121 |
Hypertriglyceridemia, n (%)* | 341 (61.2%) | 249 (58.7%) | 92 (69.2%) | 0.031 |
Low-HDL, n (%) | 357 (64.1%) | 272 (64.2%) | 85 (63.9%) | 0.960 |
Elevated fasting glucose, n (%) | 342 (61.4%) | 260 (61.3%) | 82 (61.7%) | 0.945 |
Elevated blood pressure, n (%) | 260 (46.7%) | 192 (45.3%) | 68 (51.1%) | 0.238 |
Metabolic syndrome, n (%)* | 401 (72%) | 296 (69.8%) | 105 (78.9%) | 0.041 |
CAP (dB/m)* | 273.50 ± 28.99 | 269.78 ± 27.50 | 285.38 ± 30.50 | < 0.001 |
ALT(IU/L)* | 44.90 ± 43.31 | 39.20 ± 33.58 | 63.05 ± 62.08 | < 0.001 |
FIB-4 index | 1.35 ± 0.85 | 1.37 ± 0.79 | 1.30 ± 1.04 | 0.449 |
LSM (kPa)* | 7.34 ± 3.17 | 7.09 ± 2.80 | 8.15 ± 4.05 | 0.005 |
Serious hepatic steatosis, n (%)* | 321(57.6%) | 225(53.1%) | 96(72.2%) | < 0.001 |
Elevated ALT, n (%) * | 193 (34.6%) | 124 (29.2%) | 69 (51.9%) | < 0.001 |
Advanced fibrosis n (%) | 93 (16.7%) | 67 (15.8%) | 26 (19.5%) | 0.312 |