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Table 2 Contractile activity of mouse proximal colon during acute SCFAs application in the control group

From: Short chain fatty acids and colon motility in a mouse model of irritable bowel syndrome

Concentration of SCFAs (mM)

Tonic tension (g)

Amplitude (g)

Frequency (min−1)

Sodium acetate

   

 Initial value

0.781 ± 0.011

0.735 ± 0.037

2.5 ± 0.126

 0.5

0.748 ± 0.012

0.677 ± 0.033

2.269 ± 0.116

 1

0.704 ± 0.011*

0.584 ± 0.029*

1.965 ± 0.123*

 5

0.681 ± 0.011*

0.489 ± 0.031*

1.86 ± 0.129*

 10

0.659 ± 0.011*

0.423 ± 0.028*

1.368 ± 0.101*

 30

0.621 ± 0.01*

0.378 ± 0.033*

0.565 ± 0.091*

Sodium propionate

   

 Initial value

0.84 ± 0.014

0.701 ± 0.028

2.14 ± 0.111

 0.5

0.793 ± 0.013

0.662 ± 0.03

2.003 ± 0.132

 1

0.771 ± 0.013*

0.631 ± 0.027

1.649 ± 0.095

 5

0.73 ± 0.014*

0.613 ± 0.028*

1.218 ± 0.094*

 10

0.695 ± 0.014*

0.547 ± 0.025*

0.805 ± 0.085*

 30

0.591 ± 0.007*

0.497 ± 0.014*

0.308 ± 0.081*

Butyric acid

   

 Initial value

0.861 ± 0.008

1.097 ± 0.073

2.275 ± 0.091

 0.5

0.815 ± 0.015

1.024 ± 0.077

1.537 ± 0.138

 1

0.787 ± 0.015*

0.705 ± 0.037*

0.613 ± 0.044*

 5

0.749 ± 0.015*

0.289 ± 0.02*

0.15 ± 0.032*

 10

0.682 ± 0.02*

0.152 ± 0.009*

0.061 ± 0.025*

 30

0.614 ± 0.026*

0.09 ± 0.006*

0.02 ± 0.01*

  1. *p < 0.05 compared to the initial value