TY - JOUR AU - Shaidullov, Ilnar F. AU - Sorokina, Dina M. AU - Sitdikov, Farit G. AU - Hermann, Anton AU - Abdulkhakov, Sayar R. AU - Sitdikova, Guzel F. PY - 2021 DA - 2021/01/26 TI - Short chain fatty acids and colon motility in a mouse model of irritable bowel syndrome JO - BMC Gastroenterology SP - 37 VL - 21 IS - 1 AB - Irritable bowel syndrome (IBS) is defined as a multifactorial disorder associated with visceral hypersensitivity, altered gut motility and dysfunction of the brain-gut axis. Gut microbiota and its metabolites are proposed as possible etiological factors of IBS. Short chain fatty acids (SCFAs) induce both inhibitory and stimulatory action on colon motility, however, their effects on the IBS model were not investigated. The aim of our study was to investigate the level of SFCAs in feces and their effects on colon motility in a mouse model of IBS. SN - 1471-230X UR - https://doi.org/10.1186/s12876-021-01613-y DO - 10.1186/s12876-021-01613-y ID - Shaidullov2021 ER -