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Table 2 Relative risk of micro-nutrient deficiency

From: Incidence and risk factors of micronutrient deficiency in patients with IBD and intestinal Behçet’s disease: folate, vitamin B12, 25-OH-vitamin D, and ferritin

Variable

Uni-variate analysis

Multi-variate analysis

OR (95% CI)

P-value

Adjusted OR (95% CI)

P-value

Male sex

0.842 (0.478–1.485)

0.553

0.718 (0.375–1.376)

0.319

Age

0.975 (0.958–0.993)

0.006

0.973 (0.949–0.998)

0.037

The path of laboratory test

    

 Outpatients clinic

1.0 (Ref.)

 

1.0 (Ref.)

 

 Hospitalization patients

2.204 (0.735–6.608)

0.158

2.459 (0.715–8.461)

0.154

Type of disease

    

 UC

1.0 (Ref.)

 

1.0 (Ref.)

 

 CD

3.810 (1.721–8.430)

0.001

2.492 (1.012–6.136)

0.047

 Intestinal BD

2.778 (0.734–10.513)

0.132

1.356 (0.284–6.479)

0.703

Medications

    

 5-ASA

0.381 (0.214–0.679)

0.001

0.548 (0.281–1.068)

0.077

 Steroids

0.502 (0.132–1.914)

0.313

  

 Azathioprine

1.784 (0.983–3.238)

0.057

  

 Anti-TNF

1.584 (0.900–2.788)

0.111

  

 Methotrexate

0.746 (0.340–1.637)

0.465

  

 Othersa

0.295 (0.063–1.383)

0.121

  

Operation

2.041 (1.120–3.717)

0.020

2.714 (1.260–5.844)

0.011

Underlying disease

    

 Hypertension

0.515 (0.053–5.037)

0.568

  

 Osteoporosis

0.776 (0.371–1.624)

0.501

1.500 (0.699–3.217)

0.298

 Othersb

1.131 (0.579–2.206)

0.719

2.459 (0.715–8.461)

0.154

  1. OR, odds ratio; CI, confidence interval; UC, Ulcerative colitis; CD, Crohn’s disease; BD, Behçet’s disease; 5-ASA, 5-aminosalicylic acid; anti-TNF, anti-tumor necrosis factor
  2. aMongersen, vedolizumab
  3. bMDS, SLE, AR, BOOP, OA, Osteoporosis, CAOD, cancer