Table 3 Analysis of association between rs4143370 and rs1893650 polymorphism and risk of gastric cancer
From: Analysis of the relationship between MIR155HG variants and gastric Cancer susceptibility
SNP ID | Model | Genotype | Case(N) | Control(N) | Crude | Adjusteda | ||
|---|---|---|---|---|---|---|---|---|
OR(95%CI) | p† | OR(95%CI) | p† | |||||
rs4143370 | Genotype | GG | 356 | 346 | 1 | |||
GC | 142 | 133 | 1.04 (0.79–1.37) | 0.795 | 1.04 (0.79–1.37) | 0.794 | ||
CC | 8 | 21 | 0.37 (0.16–0.85) | 0.019* | 0.37 (0.16–0.86) | 0.020* | ||
Dominant | GG | 356 | 346 | 1 | 1 | |||
GC-CC | 150 | 154 | 0.95 (0.72–1.24) | 0.690 | 0.94 (0.72–1.24) | 0.698 | ||
Recessive | GG-GC | 498 | 479 | 1 | 1 | |||
CC | 8 | 21 | 0.37 (0.16–0.84) | 0.017* | 0.37 (0.16–0.85) | 0.018* | ||
Additive | – | – | – | 0.87 (0.69–1.10) | 0.258 | 0.88 (0.69–1.11) | 0.266 | |
rs1893650 | Genotype | TT | 350 | 343 | 1 | |||
TC | 121 | 140 | 0.85 (0.64–1.13) | 0.254 | 0.85 (0.64–1.13) | 0.261 | ||
CC | 35 | 17 | 2.02 (1.11–3.67) | 0.021* | 2.01 (1.10–3.65) | 0.023* | ||
Dominant | TT | 350 | 343 | 1 | 1 | |||
TC-CC | 156 | 157 | 0.97 (1.75–1.27) | 0.845 | 0.97 (0.75–1.27) | 0.852 | ||
Recessive | TT-TC | 471 | 483 | 1 | 1 | |||
CC | 35 | 17 | 2.11 (1.17–3.82) | 0.014* | 2.10 (1.16–3.80) | 0.014* | ||
Additive | – | – | – | 1.09 (0.88–1.35) | 0.419 | 1.09 (0.88–1.35) | 0.421 | |