TY - JOUR AU - Aihara, Yosuke AU - Moriya, Kei AU - Shimozato, Naotaka AU - Nagamatsu, Shinsaku AU - Kobayashi, Shinya AU - Uejima, Masakazu AU - Matsuo, Hideki AU - Ishida, Eiwa AU - Yagi, Hideo AU - Nakatani, Toshiya AU - Yoshiji, Hitoshi AU - Kikuchi, Eiryo PY - 2021 DA - 2021/01/06 TI - Chronic active EBV infection in refractory enteritis with longitudinal ulcers with a cobblestone appearance: an autopsied case report JO - BMC Gastroenterology SP - 6 VL - 21 IS - 1 AB - Chronic active Epstein–Barr virus infection (CAEBV) is defined as Epstein–Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious mononucleocytosis, whereas enteritis and diarrhea are minor clinical symptoms. The complex mixture of tumorigenic processes of EBV-positive cells and physical symptoms of systemic inflammatory disease constitutes the varied phenotypes of CAEBV. Herein, we describe a case of CAEBV that was initially diagnosed as Crohn’s disease (CD) based on ileal ulcers and clinical symptoms of enteritis. SN - 1471-230X UR - https://doi.org/10.1186/s12876-020-01589-1 DO - 10.1186/s12876-020-01589-1 ID - Aihara2021 ER -