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Table 3 Comparison of hepatocellular carcinoma versus cholangiocarcinoma after propensity score matching

From: Clinical features and outcomes of combined hepatocellular carcinoma and cholangiocarcinoma versus hepatocellular carcinoma versus cholangiocarcinoma after surgical resection: a propensity score matching analysis

Variable

HCC (n = 43)

CC (n = 51)

p value

Male

28 (65.1)

33 (64.7)

0.213

Age (years)

59 (35–81)

60 (35–80)

0.967

Smoking

13 (30.2)

8 (15.7)

0.092

Alcohol use

11 (25.6)

4 (7.8)

0.099

HBV positive

21 (48.8)

26 (51.0)

0.836

HCV positive

9 (20.9)

18 (35.3)

0.125

Total bilirubin

0.85 ± 0.33

0.94 ± 0.46

0.241

Albumin

4.1 ± 0.4

4.2 ± 0.3

0.498

INR

1.05 ± 0.06

1.05 ± 0.12

0.912

Cirrhosis

3 (7.0)

6 (11.8)

0.432

Child–Pugh class A

39 (90.7)

51 (100)

0.058

Edmondson–Steiner Grades, I–II

5 (11.6)

12 (23.5)

0.379

Tumor size

5.7 ± 3.6

5.3 ± 2.4

0.596

Tumor size ≥ 5 cm

19 (44.4)

23 (52.3)

0.450

Tumor number (≥ 2)

1 (2.3)

2 (4.5)

0.570

AFP (ng/mL) ≥ 200

8 (18.6)

3 (5.9)

0.061

ICG%

9.2 ± 4.7

9.6 ± 5.5

0.686

Operative margin > 1 cm

24 (55.8)

30 (58.8)

0.749

Major hepatectomy

23 (53.4)

35 (68.6)

0.258

Microvascular invasion

9 (20.9)

8 (15.7)

0.510

Macrovascular invasion

6 (13.9)

1 (1.9)

0.057

Lympho nodules metastasis

2 (4.6)

8 (15.7)

0.062

Distal metastasis

0 (0)

3 (5.9)

0.106

AJCC stage, I–II

23 (60.4)

36 (70.5)

0.163

Antiviral therapy

18 (41.8)

25 (49.0)

0.186

Recurrence

16 (37.2)

6 (11.8)

0.004

Mortality

13 (30.2)

27 (52.9)

0.027

Follow up times (months)

61 (1–98)

26 (1–85)

< 0.0001

  1. Data are presented as the median (range) or number (percentage)
  2. HBV Hepatitis B virus, HCV hepatitis C virus, INR international normalized ratio, AFP alpha-fetoprotein, ICG indocyanine green, AJCC American Joint Committee on Cancer