References | Year | Location | n, IBS | n, Control | IBS diagnosis | Control Composition | Age, IBS (range, \({\overline{\text{x}}} + {\text{s}}\)) | Female IBS, n | Age, HC (range, \({\overline{\text{x}}} + {\text{s}}\)) | Female HC, n | Sample | Technique |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Yu et al. [30] | 2016 | China | 30 | 30 | Not reported | Healthy controls | 39 ± 21 | 14 | 42.5 ± 19.5 | 15 | Serum | HPLC |
Dunlop et al. [31] | 2005 | Britain | 15 | 15 | Rome II | Healthy controls | 35.1 ± 2.9 | 15 | 35.9 ± 2.6 | 10 | Plasma | HPLC |
Thijssen et al. [32] | 2015 | Netherlands | 154 | 137 | Rome III | Healthy controls | 44.5 ± 16.3 | 108 | 44.2 ± 19.3 | 84 | Plasma | HPLC |
Park et al. [29] | 2009 | Korea | 21 | 13 | Rome II | Healthy controls | 24–78 | 13 | 29–68 | 6 | Plasma | HPLC |
Keszthelyi et al. [33] | 2013 | Netherlands | 15 | 15 | Rome III | Healthy controls | 44 ± 13 | 8 | 33 ± 17 | 10 | Plasma | HPLC |