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Table 2 Different therapy in patients with early CD and late CD

From: Efficacy of early intervention on the bowel damage and intestinal surgery of Crohn’s disease, based on the Lémann index

Medical treatments

N

Inclusion LI

Follow up LI

P value

Early CD

Total

70

6.3 [1.7–10.5]

3.4 [0.6–7.4]

0.001

 IFX

42

5.5 [1.3–12.3]

2.8 [0.3–7.4]

0.01

 Other therapy

28

6.9 [2.8–8.8]

4.1 [1.4–8.0]

0.02

  Steroids + AZA

11

8.1 [6.5–12.8]

4.4 [1.8–11.0]

0.02

  Immunomodulator

9

4.3 [1.8–7.2]

3.0 [1.8–6.3]

0.61

  Enteral nutrition

2

11.0 [6.8–11.0]

7.4 [1.3–7.4]

0.18

  Mesalazine

6

4.9 [0.3–8.1]

3.6 [0.3–7.5]

0.50

Late CD

Total

84

5.9 [3.1–11.0]

5.2 [2.0–10.5]

0.71

 IFX

38

6.6 [2.7–13.6]

6.7 [2.0–12.5]

0.93

Other therapy

46

5.5 [3.2–10.3]

4.3 [2.0–9.4]

0.20

  Steroids + AZA

14

5.0 [3.7–6.5]

3.3 [2.3–8.4]

0.39

  Immunomodulator

22

6.3 [2.9–11.4]

4.9 [2.3–9.3]

0.09

  Enteral nutrition

7

10.6 [2.0–18.3]

2.4 [1.3–11.9]

0.71

  Mesalazine

3

3.2 [1.0–4.9]

9.0 [1.0–13.2]

0.18

  1. Data are expressed as median [IQR]