Skip to main content

Table 2 Different therapy in patients with early CD and late CD

From: Efficacy of early intervention on the bowel damage and intestinal surgery of Crohn’s disease, based on the Lémann index

Medical treatments N Inclusion LI Follow up LI P value
Early CD
Total 70 6.3 [1.7–10.5] 3.4 [0.6–7.4] 0.001
 IFX 42 5.5 [1.3–12.3] 2.8 [0.3–7.4] 0.01
 Other therapy 28 6.9 [2.8–8.8] 4.1 [1.4–8.0] 0.02
  Steroids + AZA 11 8.1 [6.5–12.8] 4.4 [1.8–11.0] 0.02
  Immunomodulator 9 4.3 [1.8–7.2] 3.0 [1.8–6.3] 0.61
  Enteral nutrition 2 11.0 [6.8–11.0] 7.4 [1.3–7.4] 0.18
  Mesalazine 6 4.9 [0.3–8.1] 3.6 [0.3–7.5] 0.50
Late CD
Total 84 5.9 [3.1–11.0] 5.2 [2.0–10.5] 0.71
 IFX 38 6.6 [2.7–13.6] 6.7 [2.0–12.5] 0.93
Other therapy 46 5.5 [3.2–10.3] 4.3 [2.0–9.4] 0.20
  Steroids + AZA 14 5.0 [3.7–6.5] 3.3 [2.3–8.4] 0.39
  Immunomodulator 22 6.3 [2.9–11.4] 4.9 [2.3–9.3] 0.09
  Enteral nutrition 7 10.6 [2.0–18.3] 2.4 [1.3–11.9] 0.71
  Mesalazine 3 3.2 [1.0–4.9] 9.0 [1.0–13.2] 0.18
  1. Data are expressed as median [IQR]