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Table 1 Changes in the AJCC T staging system for gastric cancer

From: The New American Joint Committee on Cancer T staging system for stomach: increased complexity without clear improvement in predictive accuracy for endoscopic ultrasound

Tumor

AJCC 6th ed.

AJCC7th ed.

AJCC8th ed.

T: Primary tumor

   

Depth of invasion

   

No evidence of primary tumor

T0

T0

T0

Carcinoma-in-situ

Tis

Tis

Tis

Lamina propria or muscularis mucosa

T1

T1

T1

Or submucosa

T1

T1

T1

Muscularis propria

T2

T2

T2

Subserosa

T2

T3

T3

Serosa

T3

T4

T4

Adjacent structures

T4

T4

T4

  1. For AJCC 6th edition: T1: tumor invasion limited to the mucosal or submucosal layer; T2: destruction of the muscularis propria or subserosal layer (T3 for AJCC 7th/8th edition); T3: cancer penetrating the serosa ((T4 for AJCC 7th/8th edition)); and T4: disease invasion in the vicinity of the stomach or other organs