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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Mixed adenoneuroendocrine carcinoma of the hepatic bile duct: a case report and review of the literature

Fig. 2

Histology and immunohistochemistry. aNeuroendocrine carcinoma and tubular adenocarcinoma [hematoxylin and eosin staining (HE), ×100]. b Cytoplasmic diffuse positive in CgA cells (DAB color development, ×200). Immunohistochemical staining. c Syncytoplasmic cytoplasmic positive, ×200. d Neuronal specific enolase (NSE) positive in neuroendocrine tumor cells, ×100. e Cytoplasmic cytokeratin 7 (CK7) diffuse positive in adenocarcinoma tumor cells, ×200. f Cell proliferation index (Ki-67) cell nucleus positive, positive rate was 70%, ×100

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