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Table 4 The frequency of coexistence of high and low HER2 gene copy number depending on the test method and the type of material tested

From: HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery

Feature HER2 gene copy number in FFPE tissue measured by qPCR
N (%)
X2
p
Below the median Above the median
HER2 gene copy number in serum (n = 57)
 Below the median (n = 29, 51%) 19 (66) 10 (34) 3.939
0.04
 Above the median (n = 28, 49%) 11 (39) 17 (60)
HER2/CEP17 ratio (n = 58)  
 R < 2.2 (n = 36, 62%) 20 (56) 16 (44) 0.07
0.79
 R ≥ 2.2 (n = 22, 38%) 13 (59) 9 (41)
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