Table 4 The frequency of coexistence of high and low HER2 gene copy number depending on the test method and the type of material tested
Feature | HER2 gene copy number in FFPE tissue measured by qPCR N (%) | X2 p | |
|---|---|---|---|
Below the median | Above the median | ||
HER2 gene copy number in serum (n = 57) | |||
Below the median (n = 29, 51%) | 19 (66) | 10 (34) | 3.939 0.04 |
Above the median (n = 28, 49%) | 11 (39) | 17 (60) | |
HER2/CEP17 ratio (n = 58) | |||
R < 2.2 (n = 36, 62%) | 20 (56) | 16 (44) | 0.07 0.79 |
R ≥ 2.2 (n = 22, 38%) | 13 (59) | 9 (41) | |