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Table 3 Univariate and Multivariate logistic regression analysis of EOGC and LOGC patients from SEER for metastasis

From: Comparison of metastasis between early-onset and late-onset gastric signet ring cell carcinoma

Variables Univariate analysis P value Multivariate analysis P value
Sex     
Male Reference Reference
Female 1.407(1.068–1.854) 0.015 1.242(0.925–1.668) 0.149
Age   0.000   
≤ 45 Reference Reference
 > 45 0.512(0.356–0.737) 0.000 0.492(0.333–0.725) 0.000
Race     
White Reference Reference
Black 0.512(0.305–0859) 0.011 0.462(0.272–0.787) 0.004
Other 0.809(0.568–1.153) 0.241 0.838(0.578–1.215) 0.351
Primary site     
Cardia Reference   
Fundus 1.13(0.314–4.075) 0.852   
Antrum 2.269(1.282–4.015) 0.005   
Body 2.365(1.193–4.689) 0.014   
Overlappping/NOS 1.341(0.699–1.553) 0.054   
T stage     
Tis/T1 Reference Reference
T2 3.766(1.271–11.16) 0.000 3.221(1.057–9.821) 0.04
T3 7.767(3.095–19.49) 0.000 5.686(2.114–15.298) 0.001
T4 21.879(8.899–53.79) 0.000 12.992(4.856–34.754) 0.000
N stage     
N0 Reference Reference
N1 1.357(0.814–2.262) 0.242 0.792(0.463–1.356) 0.395
N2 2.517(1.606–3.943) 0.000 1.242 (0.766–2.012) 0.379
N3 4.206(2.889–6.123) 0.000 1.543(1.003–2.373) 0.048
Tumor number     
1 Reference   
 > 1 0.84(0.59–1.195) 0.333   
Tumor size     
≤ 2 cm Reference Reference
≤ 5 cm 2.727(1.568–4.744) 0.000 1.273(0.692–2.34) 0.437
 > 5 cm 5.511(3.24–9.373) 0.000 1.601(0.869–2.95) 0.131
Examined LNs     
≤ 16 Reference   
 > 16 0.859(0.653–1.13) 0.278   
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