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Table 4 Univariate analyses of predictive factors associated with 6-week mortality (derivation cohort)

From: High-density lipoprotein cholesterol is a predictor of survival in cirrhotic patients with acute gastrointestinal bleeding: a retrospective study

Parameters

Univariate

Odds ratio (95% CI)

P value

Age, years

1.027 (1.003 1.052)

0.028

Male sex

1.021 (0.556 1.875)

0.947

BMI

0.900 (0.829 0.977)

0.012

Systolic blood pressure

0.959 (0.941 0.976)

0.000

Hepatocellular carcinoma

2.647 (1.549 4.522)

0.000

Heart rate

1.038 (1.024 1.052)

0.000

Hemoglobin, g/L

0.985 (0.976 0.994)

0.001

Total leukocyte count, × 109/L

1.171 (1.104 1.242)

0.000

Platelets, × 109/L

1.002 (0.998 1.006)

0.378

Alanine aminotransferase, IU/L

1.002 (1.001 1.004)

0.007

Creatinine, μmol/L

1.002 (1.000 1.004)

0.038

Sodium, mmol/L

0.817 (0.777 0.859)

0.000

Bilirubin, mmol/L

1.011 (1.008 1.014)

0.000

Albumin, g/L

0.893 (0.853 0.935)

0.000

Cholesterol, mmol/L

0.396 (0.293 0.535)

0.000

High-density lipoprotein, mmol/L

0.007 (0.002 0.020)

0.000

Low-density lipoprotein, mmol/L

0.401 (0.266 0.605)

0.000

International normalized ratio

17.48 (7.55 40.471)

0.000

Fibrinogen, g/L

0.448 (0.283 0.708)

0.001

Previous bleeding (%)

1.138 (0.666 1.946)

0.636

Ascites present (%)

3.233 (1.724 6.064)

0.000

Hepatic Encephalopathy present (%)

7.04 (3.784 13.097)

0.000

Endoscopic treatment, n (%)

0.418 (0.233 0.753)

0.004

TIPS treatment, n (%)

1.847 (0.609 5.604)

0.278

PRBC transfusion (%)

2.033 (1.202 3.441)

0.008

 > 2 PRBC transfusion (%)

1.248 (0.801 1.591)

0.066

QTc prolongation

Male (> 450 ms)

Female (> 470 ms)

2.720 (1.604 4.613)

0.000

Parameters

B

SE

Wals

Odds ratio (95% CI)

P value

Multivariate analyses: Predictors of 6-week mortality

Bilirubin, mmol/L

0.005

0.002

6.037

1.004 (1.001–1.007)

0.000

High-density lipoprotein, mmol/L

−2.757

0.662

17.331

0.063 (0.017–0.232)

0.000

Sodium, mmol/L

−0.112

0.031

12.851

0.894 (0.840–0.950)

0.000

Hemoglobin, g/L

−0.017

0.006

7.251

0.983 (0.971–0.995)

0.007

Constant

16.121

4.253

14.366

10,031,946.4

0.000