Serum hydroxybutyrate dehydrogenase as an early predictive marker of the severity of acute pancreatitis: a retrospective study

Table 2 Comparison of laboratory data between AP patients with versus without high serum HBDH levels

	ALL	High HBDH	Normal HBDH	P value
	N = 260	N = 84	N = 176	P value
WBC, × 10*9/L	12.4 ± 5.1	13.9 ± 5.6	11.7 ± 4.7	0.002**
N%	79.7 ± 13.5	83.0 ± 9.8	78.1 ± 14.8	0.007**
LDH,U/L	253.1 ± 131.1	335.9 ± 160.1	213.5 ± 91.7	< 0.001***
DB, μmol/L	6.3 ± 14.1	9.0 ± 19.8	5.0 ± 10.2	0.080*
AST, U/L	91.2 ± 145.9	130.6 ± 202.9	72.4 ± 104.3	0.015*
ALT, U/L	88.7 ± 133.7	121.2 ± 186.6	73.2 ± 95.8	0.028*
GGT, U/L	183.2 ± 273.9	269.5 ± 360.7	142.0 ± 209.9	0.003**
BUN, mmol/L	5.1 ± 2.2	5.5 ± 2.8	4.9 ± 1.9	0.046*
CRP, mg/L	33.7 ± 36.8	42.3 ± 45.1	29.6 ± 31.4	0.022*
Ca²⁺, mmol/L	2.3 ± 0.2	2.2 ± 0.2	2.3 ± 0.2	< 0.001***
Cr, μmol/L	63.5 ± 25.1	67.0 ± 33.2	61.8 ± 20.1	0.189
Glu, mmol/L	8.8 ± 0.3	9.6 ± 0.6	8.4 ± 0.4	0.066

Data are presented as the means ± standard deviation or interquartile range.*P < 0.05, **P < 0.01, ***P < 0.001. P values were determined by Student’s t-test for continuous variables and the chi-square test for categorical variables

ISSN: 1471-230X