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Table 1 Comparison of clinical characteristics and outcomes between AP patients with versus without high serum HBDH levels

From: Serum hydroxybutyrate dehydrogenase as an early predictive marker of the severity of acute pancreatitis: a retrospective study

 

ALL

High HBDH

Normal HBDH

P value

N = 260

N = 84

N = 176

Age (mean ± SD), years

51.7 ± 16.1

52.4 ± 16.6

51.3 ± 16.0

0.617

Male sex, N (%)

162 (62.3)

48 (57.1)

114 (64.8)

0.235

Smoking, N (%)

80 (30.8)

26 (31.0)

54(30.7)

0.965

Drinking, N (%)

57 (21.9)

22 (26.2)

35 (19.9)

0.251

Underlying diseases, N (%)

    

Diabetes

52 (20.0)

19 (22.6)

33 (18.8)

0.466

Hypertriglyceridemia

65 (25.0)

21 (25.0)

44 (25.0)

1.000

hypertension

93 (35.8)

36 (42.9)

57 (32.4)

0.100

NAFLD

108 (41.5)

32 (38.1)

76 (43.2)

0.436

Etiology, N (%)

   

0.241

Biliary

63 (24.2)

22 (26.2)

41 (23.3)

 

Alcohol

37 (14.2)

11 (13.1)

26 (14.8)

 

Hypertriglyceridemia

105 (40.4)

39 (46.4)

66 (37.5)

 

Others

55 (21.2)

12 (14.3)

43 (24.4)

 

Severity, N (%)

   

< 0.001***

MAP

179 (68.8)

40 (47.6)

139 (79.0)

 

MSAP

65 (25.0)

32 (38.1)

33 (18.8)

 

SAP

16 (6.2)

12 (14.3)

4 (2.3)

 

OF, N (%)

81 (31.2)

44 (52.4)

37 (21.0)

< 0.001***

SIRS, N (%)

75 (28.8)

39 (46.4)

36 (20.5)

< 0.001***

Mortality, N (%)

3 (1.2)

2 (2.4)

1 (0.6)

0.201

  1. Data are presented as the means ± standard deviation or interquartile range.*P < 0.05, **P < 0.01, ***P < 0.001. P values were determined by Student’s t-test for continuous variables and the chi-square test for categorical variables