Table 2 Correlations between clinicopathological features and MSI status in CRC
Variables | Total | MSI-H | MSS | P value |
|---|---|---|---|---|
| Â | n (%) | n (%) | n (%) | Â |
Tumor location |  |  |  | < 0.001 |
Proximal | 153 (35.6) | 41 (64.1) | 112 (30.6) | Â |
Distal | 277 (64.4) | 23 (35.9) | 254 (69.4) | Â |
Tumor size (cm) | Â | Â | Â | 0.011 |
< 5.0 | 282 (65.6) | 33 (51.6) | 249 (68.0) |  |
≥ 5.0 | 148 (34.4) | 31 (48.4) | 117 (32.0) |  |
Morphological type | Â | Â | Â | 0.717 |
Expansive | 155 (36.0) | 21 (32.8) | 134 (36.6) | Â |
Infiltrative | 20 (4.7) | 4 (6.3) | 16 (4.4) | Â |
Ulcerative | 255 (59.3) | 39 (60.9) | 216 (59.0) | Â |
Histological type |  |  |  | < 0.001 |
Non-mucinous | 364 (84.7) | 42 (65.6) | 322 (88.0) | Â |
Mucinous | 66 (15.3) | 22 (34.4) | 44 (12.0) | Â |
Histological grade | Â | Â | Â | 0.008 |
Well/moderately differentiated | 308 (71.6) | 37 (57.8) | 271 (74.0) | Â |
Poorly differentiated | 122 (28.4) | 27 (42.2) | 95 (26.0) | Â |
Lymphatic invasion | Â | Â | Â | 0.030 |
Absent | 331 (77.0) | 56 (87.5) | 275 (75.1) | Â |
Present | 99 (23.0) | 8 (12.5) | 91 (24.9) | Â |
T classification | Â | Â | Â | 0.811 |
T1 + T2 | 63 (14.7) | 10 (15.6) | 53 (14.5) |  |
T3 + T4 | 367 (85.3) | 54 (84.4) | 313 (85.5) |  |
Lymph node metastasis | Â | Â | Â | 0.010 |
Absence | 267 (62.1) | 49 (76.6) | 218 (59.6) | Â |
Presence | 163 (37.9) | 15 (23.4) | 148 (40.4) | Â |
Distant metastasis | Â | Â | Â | 0.713 |
Absence | 382 (88.8) | 56 (87.5) | 326 (89.1) | Â |
Presence | 48 (11.2) | 8 (12.5) | 40 (10.9) | Â |
Stage | Â | Â | Â | 0.003 |
I–II | 258 (60.0) | 49 (76.6) | 209 (57.1) |  |
III–IV | 172 (40.0) | 15 (23.4) | 157 (42.9) |  |