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Table 4 Clinical intervention characteristics

From: The effects of resistant starches on inflammatory bowel disease in preclinical and clinical settings: a systematic review and meta-analysis

References Type of RS Source of RS Dose of RS Frequency and duration of administration Concomitant therapies Wash-out period
James et al. [49] RS1, RS2 HAMS added to bread, cereal and muffins 5 g (low dose)
15 g (high dose)
In diet for 17 days (3 day ramp-up period of 25% of total increase per day) Aminosalicylates immunomodulators Corticosteroids
14 days
Clarke et al. [48] RS 2 HAMS added to milk-based chocolate custards 20 g Daily for 6 days None None
Hanai et al. [46] RS 1 GBF, unclear administration 6.4 g In diet daily for 12 months Aminosalicylates
Hallert et al. [47] RS 1 4 slices of oat bran–enriched bread and 37 mL of oat bran suspended in water, juice, or yogurt 0.6 g In diet daily for 12 weeks Aminosalicylates
Corticosteroids Immunosuppressive agent
Kanauchi et al. [38, 45] RS 1 GBF 6.4–10.2 g In diet daily for 24 weeks Aminosalicylates
Silvester et al. [43] RS 2, RS3 13 different foods with about three-quarters of the amount fed in the MRS and HRS test diets from potato flour biscuits and bananas High: 34.8 g (32.9–36.0)
Medium: 17.3 g (16.5–17.9)
Low: 2.9 g (2.6–3.2)
Potato flour: 11.8 g
Diet period was 5 days (control, low, medium, high, potato for 1 day each) Naproxen NR
Mitsuyama et al. [44] RS 1 GBF, oral administration 10.2 g Daily (split 3 times a day) for 4 weeks Aminosalicylates
  1. GBF germinated barley foodstuff, HAMS high-amylose maize starch, N/A not applicable