Fig. 6
From: Changes in plasma bile acids are associated with gallbladder stones and polyps
The possible mechanism of UDCA in GBD treatment. UDCA is attractive drug candidates for the treatment of GBD, since it may affect inflammatory response, unique BA profile and intestinal microbial community structure. BAs may also alter the influence of oestrogen on cholesterol metabolism, explaining why females suffer more from GDB than males. Furthermore, hypertension and obesity may serve as risk predictors of GBD. This figure was created by the author (Xunxia Bao)