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Table 3 Comparison of clinicopathologic factors of early gastric cardiac with or without oesophageal invasion

From: Distinct clinicopathological differences between early gastric cardiac and non-cardiac carcinomas: a single-center retrospective study of 329 radical resection cases

Clinicopathologic factor Oesophageal invasion Total P value
Without With
Number 48 22 (1–10 mm, 4.16 ± 2.82 mm) 70 NS
Gender     
 Male 37 (77.1) 13 (59.1) 50 (71.4) NS
 Female 11 (22.9) 9 (40.9) 20 (28.6)  
 M/F ratio 3.36 1.44 2.50  
Age (year)     
 ≤ 40 0 (0) 0 0 NS
 41–69 35 (72.9) 19 (86.4) 54 (77.1)  
 ≥ 70 13 (27.1) 3 (13.6) 16 (22.9)  
 Average (SD) 64.44 ± 7.57 63.14 ± 7.88 64.03 ± 7.63 NS
Origin     
 Gastric 48 (100) 22 (100) 70 (100) NS
 Oesophagus 0 (0) 0 (0) 0 (0)  
Metaplasia     
 Without 14 (29.2) 6 (27.3)) 20 (28.6) NS
 Columnar cell 23 (47.9) 11 (50.0) 34 (48.6)  
 Pancreatic 10 (20.8) 3 (13.6) 13 (18.6)  
 Goblet cell 1 (2.1) 2 (9.1) 3 (4.3)  
Macroscopic feature     
 I 3 (6.3) 2 (9.1) 5 (7.1) NS
 IIa 2 (4.2) 0 (0) 2 (2.9)  
 IIb 10 (20.8) 6 (27.3) 16 (22.9)  
 IIc 17 (35.4) 6 (27.3) 23 (32.9)  
 III 16 (33.3) 8 (36.4) 24 (34.3)  
 I + IIa 5 (10.4) 2 (9.1) 7 (10.0) NS
 IIb 10 (20.8) 6 (27.3) 16 (22.9)  
 IIc + III 33 (68.8)31 14 (63.6) 47 (67.1)  
Size (cm)     
 ≤ 0.9 10 (20.8) 2 (9.1) 12 (17.1) NS
 1–1.9 21 (43.8) 5 (22.7) 26 (37.1)  
 2–2.9 12 (25.0) 8 (36.4) 20 (28.6)  
 > 3 5 (10.4) 7 (31.8) 12 (17.1)  
Invasion depth     
 M2 7 (14.6) 2 (9.1) 9 (12.9)) NS
 M3 14 (29.2) 5 (22.7) 19 (27.1)  
 SM1 7 (14.6) 3 (13.6) 10 (14.3)  
 SM2 20 (41.7) 12 (54.5) 32 (45.7)  
Histology type     
 Tubular adenocarcinoma 32 (66.7) 8 (36.4) 40 (57.1) < 0.05
 Papillary adenocarcinoma 7 (14.6) 6 (27.3) 13 (18.6)  
 Micropapillary adenocarcinomaa 1 (2.1) 0 (0) 1 (1.4)  
 Poorly cohesive carcinoma 1 (2.1) 1 (4.5) 2 (2.8)  
 Mucinous carcinoma 1 (2.1) 0 (0) 1 (1.4)  
 Mixed PCC and adenocarcinoma 3 (6.3) 3 (13.6) 6 (8.6)  
 Mixed mucinous and tubular adenocarcinoma 1 (2.1) 2 (9.1) 3 (4.3)  
 Neuroendocrine/medullary /adenosquamous/clear cell carcinoma 2 (4.2) 2 (9.1) 4 (5.7)  
Differentiation     
 Well 13 (27.1) 4 (18.2) 17 (24.3) NS
 Moderate 28 (58.3) 14 (63.6) 42 (60.0)  
 Poorly 7 (14.6) 4 (18.2) 11 (15.7)  
Lymphovascular invasion     
 Absence 42 (87.5) 17 (77.3) 59 (84.3) NS
 Presence 6 (12.5) 5 (22.7) 11 (15.7)  
Perineural invasion     
 Absence 46 (95.8) 21 (95.5) 67 (95.7) NS
 Presence 2 (4.2) 1 (4.5) 3 (4.3)  
Lymph node metastasis     
 Absence 43 (89.6) 20 (90.9) 63 (90.0) NS
 Presence 5 (10.4)) 2 (9.1) 7 (10.0)  
 N1 4 (8.3) 1 (4.5) 5 (7.1)  
 N2 1 (2.1) 0 (0) 1 (1.4)  
 N3 0 (0.0) 1 (4.5) 1 (1.4)  
  1. SD standard deviation, PCC poorly cohesive carcinoma, NS not significant
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