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Table 3 Multivariate analysis for overall survival (OS) and cancer-specific survival (CSS) among patients with small bowel adenocarcinoma who had liver metastasis

From: Frequency, prognosis and treatment modalities of newly diagnosed small bowel cancer with liver metastases

Variables

OS

CSS

HR (95% CI)

P value

HR (95% CI)

P value

Age

 < 40

Reference

 

Reference

 

 40–59

0.81 (0.48–1.36)

0.417

0.77 (0.45–1.29)

0.312

 60–79

0.95 (0.58–1.58)

0.854

0.83 (0.50–1.37)

0.461

 ≥ 80

1.52 (0.89–2.62)

0.129

1.39 (0.80–2.40)

0.241

Race

 Black

Reference

 

Reference

 

 White

1.14 (0.90–1.45)

0.262

1.15 (0.90–1.48)

0.255

 Othersa

1.00 (0.66–1.52)

0.988

1.09 (0.71–1.67)

0.687

Primary site

 Duodenum

Reference

 

Reference

 

 Jejunum

0.65 (0.46–0.92)

0.014

0.61 (0.43–0.88)

0.008

 Ileum

0.81 (0.55–1.21)

0.307

0.86 (0.57–1.28)

0.453

 Other siteb

0.42 (0.15–1.15)

0.090

0.46 (0.17–1.27)

0.133

 Unknown

0.96 (0.72–1.27)

0.774

0.97 (0.72–1.29)

0.810

T stage

 T1

Reference

 

Reference

 

 T2

1.36 (0.62–2.98)

0.445

1.52 (0.69–3.35)

0.299

 T3

0.77 (0.53–1.11)

0.165

0.75 (0.51–1.11)

0.155

 T4

1.02 (0.76–1.37)

0.888

1.02 (0.75–1.38)

0.913

 Unknown

1.30 (0.99–1.70)

0.061

1.37 (1.03–1.82)

0.031

N stage

 N0

Reference

 

Reference

 

 N1

0.93 (0.74–1.16)

0.516

0.94 (0.75–1.19)

0.600

 N2

0.93 (0.66–1.32)

0.686

0.98 (0.68–1.40)

0.895

 Unknown

0.96 (0.73–1.27)

0.793

0.93 (0.69–1.24)

0.604

  1. CI confidence interval, HR hazard ratio
  2. aAsian and American Indians
  3. bMeckels diverticulum, and overlapping lesion of small intestine