Table 6 Association of combined Ki-67 and Her2 expression with pT and pN stages in patients with non-metastatic gastric cancer estimated using univariable and multivariable-adjusted logistic regression
Ki-67 and Her2 expression | Association with pT | Association with pN | ||
|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | |
Univariable testa | ||||
 Her2 negative and Ki-67 negative | 1 (reference) |  | 1 (reference) |  |
 Her2 negative and Ki-67 positive | 0.22 (0.06–0.76) | 0.035 | 0.84 (0.45–1.58) | 0.819 |
 Her2 positive and Ki-67 negative | 0.14 (0.03–0.59) | 0.012 | 0.62 (0.24–1.57) | 0.404 |
 Her2 positive and Ki-67 positive | 0.13 (0.03–0.51) | 0.009 | 0.81 (0.37–1.78) | 0.985 |
Multivariable test 1b | Model 1 | Â | Model 2 | Â |
 Her2 negative and Ki-67 negative | 1 (reference) |  | 1 (reference) |  |
 Her2 negative and Ki-67 positive | 0.14 (0.03–0.61) | 0.044 | 1.08 (0.56–2.08) | 0.673 |
 Her2 positive and Ki-67 negative | 0.11 (0.02–0.64) | 0.029 | 1.21 (0.44–3.34) | 0.942 |
 Her2 positive and Ki-67 positive | 0.07 (0.01–0.39) | 0.025 | 1.48 (0.62–3.55) | 0.429 |
Multivariable test 2c | Model 3 | Â | Model 4 | Â |
 Her2 negative and Ki-67 negative | 1 (reference) |  | 1 (reference) |  |
 Her2 negative and Ki-67 positive | 0.13 (0.03–0.64) | 0.039 | 1.27 (0.65–2.49) | 0.601 |
 Her2 positive and Ki-67 negative | 0.07 (0.01–0.48) | 0.015 | 1.64 (0.57–4.74) | 0.706 |
 Her2 positive and Ki-67 positive | 0.06 (0.01–0.37) | 0.009 | 2.01 (0.80–5.00) | 0.263 |