Predictors | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR(95% CI) | P-value | HR(95% CI) | P-value | |
Age (years) | 0.996 (0.980 to 1.013) | 0.676 | Â | Â |
BMI (kg/m2) | 1.028 (0.979 to 1.078) | 0.268 | Â | Â |
MAP (mmHg) | 1.001 (0.985 to 1.018) | 0.901 | Â | Â |
Laboratory data | ||||
 WBC count (109/L) | 1.038 (1.010 to 1.066) | 0.007 |  |  |
 Platelet count(109/L) | 0.998 (0.995 to 1.002) | 0.306 |  |  |
 Total bilirubin (μmol/L) | 1.000 (0.999 to 1.001) | 0.498 |  |  |
 Albumin(g/L) | 0.998 (0.967 to 1.030) | 0.913 |  |  |
 INR | 1.755 (1.455 to 2.118) | < 0.001 | 1.482 (1.229 to 1.788) | < 0.001 |
 Creatinine (μmol/L) | 1.001 (1.000 to 1.003) | 0.105 |  |  |
 Serum sodium (mmol/L) | 0.983 (0.955 to 1.011) | 0.233 |  |  |
 HBV-DNA level (IU/ml) | ||||
   ≤ 200 | 1 | 0.126 |  |  |
  200–2 × 104 | 0.599 (0.341 to 1.051) | 0.074 |  |  |
 2 × 104–2 × 106 | 0.864 (0.528 to 1.415) | 0.562 |  |  |
   ≥ 2 × 106 | 1.151 (0.694 to 1.911) | 0.586 |  |  |
SIRS | 1.658 (1.136 to 2.421) | 0.009 | Â | Â |
Type of infection(%) | ||||
 Pneumonia | 2.315 (1.563 to 3.429) | < 0.001 | 1.904 (1.268 to 2.860) | 0.002 |
 SBP | 0.623 (0.429 to 0.904) | 0.013 |  |  |
 Bacteremia | 1.260 (0.815 to 1.949) | 0.299 |  |  |
Number of infection sites | ||||
 One | 1 | 0.132 |  |  |
 Two | 1.184 (0.778 to 1.803) | 0.430 |  |  |
 Three or more | 1.718 (1.008 to 2.926) | 0.046 |  |  |
Number of isolated microorganisms | ||||
 Zero | 1 | 0.638 |  |  |
 One | 0.941 (0.625 to 1.418) | 0.773 |  |  |
 Two | 0.911 (0.456 to 1.819) | 0.791 |  |  |
 Three or more | 1.375 (0.749 to 2.524) | 0.304 |  |  |
Complications(%) | ||||
 Ascites | 0.777 (0.585 to 1.031) | 0.081 |  |  |
 Hemorrhage | 1.447 (0.885 to 2.367) | 0.141 |  |  |
 Acute kidney injury | 1.456 (1.001 to 2.117) | 0.049 | 1.529 (1.046 to 2.235) | 0.028 |
 HE | 1.409 (1.214 to 1.636) | < 0.001 | 1.263 (1.087 to 1.466) | 0.002 |
Sepsis(%) | 2.740 (1.756 to 4.273) | < 0.001 | 2.166 (1.372 to 3.421) | 0.001 |
Septic shock(%) | 2.322 (1.612 to 3.345) | < 0.001 |  |  |