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Table 3 Characteristics of the infection-related index of different infection sites and pathogens

From: Infection deteriorating hepatitis B virus related acute-on-chronic liver failure: a retrospective cohort study

Variables N WBC(109/L) N(%) CRP (mg/L) PCT (ng/ml) SIRS(%) Sepsis(%) Septic shock(%) ACLF-1(%): ACLF-2(%): ACLF-3(%) 28-day mortality(%)
Type of infections
 Pneumonia alone 52 10.3 (7.3,13.6) 82 (72,89) 16.4 (11.0,54.7) 1.4 (0.8,4.4) 16 (30.8) 33 (63.5) 19 (36.5) 10 (19.2): 25 (48.1): 17 (32.7) 42 (80.8)
 SBP alone 37 9.1 (5.8,13.1) 79 (67,85) 17.5 (8.8,51.2) 1.0 (0.5,1.6) 14 (37.8) 17 (45.9) 6 (16.2) 12 (32.4): 20 (54.1): 5 (13.5) 12 (32.4)
 Bacteraemia alone 10 11.1 (6.6,15.5) 71 (65,82) 41.0 (24.5,59.2) 2.2 (1.0,4.6) 3 (30.0) 6 (60.0) 2 (20.0) 4 (40.0): 4 (40.0): 2 (20.0) 6 (60.0)
 Othersa 16 8.7 (4.8,14.9) 73 (62,82) 26.4 (9.4,68.6) 1.1 (0.5,5.0) 5 (31.3) 10 (62.5) 4 (25.0) 5 (31.3): 9 (56.3): 2 (12.5) 8 (50.0)
Number of infection sites
 One 115 9.9 (6.5,13.5) 79 (68,86) 18.9 (11.2,53.0) 1.4 (0.5,2.8) 38 (33.0) 66 (57.4)** 31 (27.0)*** 31 (27.0): 58 (50.4): 26 (22.6)* 68 (59.1)
 Two 50 9.2 (5.1,13.7) 81 (74,87) 19.0 (10.9,69.5) 1.5 (0.6,4.1) 17 (34.0) 39 (78.0) 24 (48.0) 22 (44.0): 18 (36.0):10 (20.0) 32 (64.0)
 Three or more 20 12.9 (6.9,21.8) 81 (76,84) 55.6 (10.1,99.5) 0.9 (0.7,4.9) 8 (40.0) 17 (85.0) 14 (70.0) 9 (45.0): 4 (20.0): 7 (35.0) 17 (85.0)
Type of pathogens
 G- alone 42 8.9 (7.0,12.8) 79 (70,88) 29.3 (13.6,73.9) 1.6 (0.8,4.9) 14 (33.3) 25 (59.5) 13 (31.0) 18 (42.9): 18 (42.9): 6 (14.3) 25 (59.5)
 G+ alone 26 10.7 (7.5,15.5) 79 (74,86) 34.0 (14.4,87.3) 1.5 (0.6,2.8) 10 (38.5) 16 (61.5) 5 (19.2) 8 (30.8): 12 (46.2): 6 (23.1) 15 (57.7)
 Fungus alone 23 10.3 (5.7,15.1) 79 (69,88) 20.4 (9.3,55.0) 1.5 (0.9,4.5) 7 (30.4) 11 (47.8) 4 (17.4) 7 (30.4): 10 (43.5): 6 (26.1) 15 (65.2)
Number of strains
 One 86 9.7 (6.6,13.0) 79 (70,87) 27.6 (13.5,65.7) 1.5 (0.9,4.5) 29 (33.7) 49 (57.0)** 21 (24.4)*** 30 (34.9): 39 (45.3): 17 (19.8) 52 (60.5)
 Two 16 10.0 (6.0,14.8) 80 (72,88) 10.9 (7.2,71.3) 1.1 (0.5,2.8) 6 (37.5) 12 (75.0) 9 (56.3) 5 (31.3): 8 (50.0): 3 (18.8) 10 (62.5)
 Three or more 18 12.6 (6.5,21.0) 82 (74,88) 55.2 (9.6,94.5) 1.2 (0.5,5.9) 6 (33.3) 18 (100.0) 17 (94.4) 5 (27.8): 5 (27.8): 8 (44.4) 14 (77.8)
  1. Note: All data are expressed as number (%) or median (IQR)
  2. Abbreviations: N number, WBC white blood cells, N(%) percentage of neutrophils, CRP C-reactive protein, PCT procalcitonin, SIRS system inflammatory reaction syndrome, ACLF acute-on-chronic liver failure, SBP spontaneous bacterial peritonitis, G- Gram-negative bacteria, G+ Gram-positive bacteria
  3. aOther infections included urinary tract infection alone (8): skin and soft tissue infection alone (1): infections diarrhea alone (2): spontaneous bacterial empyema alone (1): the undefined infection alone (4)
  4. *P-value< 0.05
  5. **P-value< 0.01
  6. ***P-value< 0.001
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