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Table 3 Characteristics of the infection-related index of different infection sites and pathogens

From: Infection deteriorating hepatitis B virus related acute-on-chronic liver failure: a retrospective cohort study

Variables

N

WBC(109/L)

N(%)

CRP (mg/L)

PCT (ng/ml)

SIRS(%)

Sepsis(%)

Septic shock(%)

ACLF-1(%): ACLF-2(%): ACLF-3(%)

28-day mortality(%)

Type of infections

 Pneumonia alone

52

10.3 (7.3,13.6)

82 (72,89)

16.4 (11.0,54.7)

1.4 (0.8,4.4)

16 (30.8)

33 (63.5)

19 (36.5)

10 (19.2): 25 (48.1): 17 (32.7)

42 (80.8)

 SBP alone

37

9.1 (5.8,13.1)

79 (67,85)

17.5 (8.8,51.2)

1.0 (0.5,1.6)

14 (37.8)

17 (45.9)

6 (16.2)

12 (32.4): 20 (54.1): 5 (13.5)

12 (32.4)

 Bacteraemia alone

10

11.1 (6.6,15.5)

71 (65,82)

41.0 (24.5,59.2)

2.2 (1.0,4.6)

3 (30.0)

6 (60.0)

2 (20.0)

4 (40.0): 4 (40.0): 2 (20.0)

6 (60.0)

 Othersa

16

8.7 (4.8,14.9)

73 (62,82)

26.4 (9.4,68.6)

1.1 (0.5,5.0)

5 (31.3)

10 (62.5)

4 (25.0)

5 (31.3): 9 (56.3): 2 (12.5)

8 (50.0)

Number of infection sites

 One

115

9.9 (6.5,13.5)

79 (68,86)

18.9 (11.2,53.0)

1.4 (0.5,2.8)

38 (33.0)

66 (57.4)**

31 (27.0)***

31 (27.0): 58 (50.4): 26 (22.6)*

68 (59.1)

 Two

50

9.2 (5.1,13.7)

81 (74,87)

19.0 (10.9,69.5)

1.5 (0.6,4.1)

17 (34.0)

39 (78.0)

24 (48.0)

22 (44.0): 18 (36.0):10 (20.0)

32 (64.0)

 Three or more

20

12.9 (6.9,21.8)

81 (76,84)

55.6 (10.1,99.5)

0.9 (0.7,4.9)

8 (40.0)

17 (85.0)

14 (70.0)

9 (45.0): 4 (20.0): 7 (35.0)

17 (85.0)

Type of pathogens

 G- alone

42

8.9 (7.0,12.8)

79 (70,88)

29.3 (13.6,73.9)

1.6 (0.8,4.9)

14 (33.3)

25 (59.5)

13 (31.0)

18 (42.9): 18 (42.9): 6 (14.3)

25 (59.5)

 G+ alone

26

10.7 (7.5,15.5)

79 (74,86)

34.0 (14.4,87.3)

1.5 (0.6,2.8)

10 (38.5)

16 (61.5)

5 (19.2)

8 (30.8): 12 (46.2): 6 (23.1)

15 (57.7)

 Fungus alone

23

10.3 (5.7,15.1)

79 (69,88)

20.4 (9.3,55.0)

1.5 (0.9,4.5)

7 (30.4)

11 (47.8)

4 (17.4)

7 (30.4): 10 (43.5): 6 (26.1)

15 (65.2)

Number of strains

 One

86

9.7 (6.6,13.0)

79 (70,87)

27.6 (13.5,65.7)

1.5 (0.9,4.5)

29 (33.7)

49 (57.0)**

21 (24.4)***

30 (34.9): 39 (45.3): 17 (19.8)

52 (60.5)

 Two

16

10.0 (6.0,14.8)

80 (72,88)

10.9 (7.2,71.3)

1.1 (0.5,2.8)

6 (37.5)

12 (75.0)

9 (56.3)

5 (31.3): 8 (50.0): 3 (18.8)

10 (62.5)

 Three or more

18

12.6 (6.5,21.0)

82 (74,88)

55.2 (9.6,94.5)

1.2 (0.5,5.9)

6 (33.3)

18 (100.0)

17 (94.4)

5 (27.8): 5 (27.8): 8 (44.4)

14 (77.8)

  1. Note: All data are expressed as number (%) or median (IQR)
  2. Abbreviations: N number, WBC white blood cells, N(%) percentage of neutrophils, CRP C-reactive protein, PCT procalcitonin, SIRS system inflammatory reaction syndrome, ACLF acute-on-chronic liver failure, SBP spontaneous bacterial peritonitis, G- Gram-negative bacteria, G+ Gram-positive bacteria
  3. aOther infections included urinary tract infection alone (8): skin and soft tissue infection alone (1): infections diarrhea alone (2): spontaneous bacterial empyema alone (1): the undefined infection alone (4)
  4. *P-value< 0.05
  5. **P-value< 0.01
  6. ***P-value< 0.001