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Table 3 SNP associated with the development of nonalcoholic fatty liver disease

From: The association of genetic polymorphisms with nonalcoholic fatty liver disease in a longitudinal study

 

Discovery

Validation

SNP

Chr

Position

Nearest Genes

Risk

Allele

Risk allele Frequency

HR

(95% CI)

P-value

Risk allele Frequency

HR

(95% CI)

P-value

rs4906353

14

104,127,246

KCL1

T

0.030

0.72

(0.61, 0.85)

9.68E-5

0.026

0.65

(0.48, 0.88)

0.00531

  1. SNP single-nucleotide polymorphism, Chr chromosome number, HR hazard ratio, CI confidence interval, KCL kinesin light chain
  2. P values are adjusted for age, sex and body mass index. An additive genetic model was used
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BMC Gastroenterology

ISSN: 1471-230X

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