Table 1 Baseline characteristics of the study population
Discovery set (N = 4201) | Validation set (N = 1522) | P-Value | |
|---|---|---|---|
Age (years) | 49.7 ± 10.2 | 49.3 ± 9.8 | 0.158 |
Male, n (%) | 2259 (53.8) | 878 (57.7) | 0.009 |
Diabetes mellitus, n (%) | 194 (4.6) | 77 (5.1) | 0.487 |
Hypertension, n (%) | 675 (16.1) | 256 (16.8) | 0.496 |
Systolic blood pressure (mmHg) | 114.6 ± 13.2 | 115.6 ± 13.0 | 0.010 |
Diastolic blood pressure (mmHg) | 75.1 ± 10.2 | 76.3 ± 9.9 | < 0.001 |
Body mass index (kg/m2) | 22.9 ± 3.0 | 23.2 ± 3.0 | 0.003 |
Waist circumference (cm) | 82.2 ± 8.7 | 82.1 ± 8.7 | 0.749 |
AST (IU/L) | 22.6 ± 9.5 | 23.0 ± 10.4 | 0.198 |
ALT (IU/L) | 22.3 ± 15.0 | 23.5 ± 17.0 | 0.017 |
Total cholesterol (mg/dL) | 192.6 ± 33.7 | 194.6 ± 34.0 | 0.046 |
Triglyceride (mg/dL) | 105.5 ± 68.2 | 107.7 ± 72.0 | 0.313 |
High-density lipoprotein cholesterol (mg/dL) | 53.8 ± 12.0 | 53.9 ± 12.0 | 0.637 |
Fasting glucose (mg/dL) | 97.5 ± 15.0 | 99.3 ± 19.3 | 0.001 |
Development of NAFLD, n (%) | 643 (22.1) | 231 (23.1) | 0.554 |
Regression of NAFLD, n (%) | 240 (18.5) | 96 (18.5) | 0.989 |