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Table 1 Baseline characteristics of the study population

From: The association of genetic polymorphisms with nonalcoholic fatty liver disease in a longitudinal study

  Discovery set
(N = 4201)
Validation set
(N = 1522)
P-Value
Age (years) 49.7 ± 10.2 49.3 ± 9.8 0.158
Male, n (%) 2259 (53.8) 878 (57.7) 0.009
Diabetes mellitus, n (%) 194 (4.6) 77 (5.1) 0.487
Hypertension, n (%) 675 (16.1) 256 (16.8) 0.496
Systolic blood pressure (mmHg) 114.6 ± 13.2 115.6 ± 13.0 0.010
Diastolic blood pressure (mmHg) 75.1 ± 10.2 76.3 ± 9.9 < 0.001
Body mass index (kg/m2) 22.9 ± 3.0 23.2 ± 3.0 0.003
Waist circumference (cm) 82.2 ± 8.7 82.1 ± 8.7 0.749
AST (IU/L) 22.6 ± 9.5 23.0 ± 10.4 0.198
ALT (IU/L) 22.3 ± 15.0 23.5 ± 17.0 0.017
Total cholesterol (mg/dL) 192.6 ± 33.7 194.6 ± 34.0 0.046
Triglyceride (mg/dL) 105.5 ± 68.2 107.7 ± 72.0 0.313
High-density lipoprotein cholesterol (mg/dL) 53.8 ± 12.0 53.9 ± 12.0 0.637
Fasting glucose (mg/dL) 97.5 ± 15.0 99.3 ± 19.3 0.001
Development of NAFLD, n (%) 643 (22.1) 231 (23.1) 0.554
Regression of NAFLD, n (%) 240 (18.5) 96 (18.5) 0.989
  1. Data are shown as the mean ± SD
  2. AST aspartate aminotransferase, ALT alanine aminotransferase, NAFLD nonalcoholic fatty liver disease