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Table 3 Baseline demographic and clinical characteristics of the patients evaluated for liver transplantation (LT) for complications of cirrhosis among patients who; (i) were alive at last follow up without LT, (ii) died without LT or (iii) underwent LT. Data are shown as mean ± standard deviation or percentage

From: Extra-hepatic comorbidity burden significantly increases 90-day mortality in patients with cirrhosis and high model for endstage liver disease

Demographic and clinical characteristics

Survived without LT

n = 54

Died without LT

n = 186

Underwent LT

n = 100a

P-value

Age

54 ± 10

57 ± 9

56 ± 10

0.14

Gender (male) (%)

43

64

71

0.002

Race (%)

 White

87

91

91

0.4

 Black

4

4

6

 Hispanic

6

4

1

 Asian

None

1

1

 Other

3

None

1

Body mass index

28 ± 6

30 ± 7

30 ± 6

0.4

Etiology of liver disease (%)

 Alcohol

29

34

30

0.001

 Alcohol and viral

12

21

10

 Viral

29

18

13

 Autoimmune

9

2

17

 Fatty liver

19

20

24

 Cryptogenic

2

2

3

 MELD

13.9 ± 4.4

17.7 ± 7.1

18.1 ± 5.9

< 0.001

 Hepatocellular carcinoma (%)

7

27

25

0.01

CCI (mean)

0.6 ± 0.9

1.1 ± 1.3

0.6 ± 0.8

< 0.001

 (median (IQR))

0 (IQR 0,1)

1 (IQR 0,2)

0 (IQR 0,1)

CCI Category (%)

 CCI = 0

59

34

56

0.001

 CCI = 1–2

33

50

38

 CCI > 2

8

16

6

CIRCOM

0.6 ± 0.8

0 (IQR 0,1)

1.1 ± 1.3

1 (IQR 0,2)

0.4 ± 0.9

0 (IQR 0,1)

< 0.001

  1. Abbreviations: CCI cirrhosis-modified Charlson Comorbidity Index (excluding liver disease and liver cancer), IQR interquartile range, MELD-Na Model for End-stage Liver Disease with sodium modification
  2. Footnotes: a includes one patient who underwent LT at another center