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Table 3 Frequency of GI symptoms in pediatric patients with low disaccharidase activity

From: A retrospective study on the association of gastrointestinal symptoms in children with low lactase activity and low activity of other disaccharidases

Low Activity Groups Total Presenting Symptom Frequencies1
Abdominal Pain Diarrhea Weight Loss Reflux
  N % N % N % N % N %
Total Population 347 100.0 223 64.3 97 28.0 39 11.2 119 34.3
Total Normal Activity 174 50.1 101 58.4 56 32.4 23 13.3 59 34.1
Any Low Activity2 173 49.9 122 70.5 40 23.1 16 9.2 60 34.7
Low Beta-Glucosidase alone
Lactase Alone 111 32.0 79 71.2 27 24.3 7 6.3 39 35.1
Low Beta-Glucosidase + Low Alpha-Glucosidases Combined
 Sucrase+Lactase 5 1.4 4 80.0 2 40.0 1 20.0 1 20.0
 Maltase+Lactase 16 4.6 11 68.8 5 31.3 1 6.3 7 43.8
 Sucrase+Lactase+Maltase 24 6.9 16 66.7 6 25.0 5 20.8 10 41.7
 Pandissacharidase3 8 2.3 7 87.5 1 12.5 0 0.0 1 12.5
Total 53 15.3 38 71.7 14 26.4 7 13.2 19 35.8
Low Alpha-Glucosidases alone
 Maltase alone 3 0.9 1 33.3 0 0.0 1 33.3 1 33.3
 Maltase+Sucrase 4 1.2 4 100.0 0 0.0 0 0.0 0 0.0
 Sucrase+Maltase+Palatinase 2 0.6 0 0.0 0 0.0 2 100.0 0 0.0
Total 9 2.6 5 55.6 0 0.0 3 33.3 1 11.1
  1. 1Percentages in the “Presenting Symptom Frequencies” columns are percentages of N of the “Total” column. Patients with multiple GI symptoms were included in more than one symptom category per specific disaccharidase
  2. 2Reference values are 15, 25, 100 and 5 μM/min/g protein for lactase, sucrase, maltase and palatinase respectively
  3. 3Pandisaccharidase = Maltase+Sucrase+Lactase+Palatinase