Factors contributing to diagnostic delay of Caroli syndrome: a single-center, retrospective study

BMC Gastroenterology

Table 1 Association between ln (diagnostic delay) and demographics, initial symptoms, laboratory findings, and image modalities used

	N	Mean	SD	P-value
Ln (DD)
Male	10	0.76	1.74
Female	6	0.17	2.20	p = 0.56
^aAge of onset of symptoms				p = 0.52
^aAge of first clinical visit				p = 0.99
^aAge of diagnosis				p = 0.17
^bFever	6	0.41	2.31
Not fever	10	0.61	1.70	p = 0.84
^bAbdominal pain	3	0.63	1.51
Not abdominal pain	13	0.52	2.00	p = 0.93
^bAbdominal distention	8	0.84	1.39
Not abdominal distention	8	0.23	2.32	p = 0.54
Normal WBC	5	−1.47	1.36
Decreased WBC	11	1.45	1.27	p = 0.01
Normal HGB	5	−0.47	1.57
Decreased HGB	11	0.99	1.89	p = 0.16
Normal PLT	6	−0.92	1.80
Decreased PLT	10	1.41	1.34	p = 0.01
No pancytopenia	6	−0.92	1.80
Pancytopenia	10	1.41	1.34	p = 0.01
Normal PT	11	0.51	2.16
Prolonged PT	5	0.59	1.25	p = 0.94
CT at first hospital visited	8	−0.55	1.76
No CT at first hospital visited	8	1.62	1.33	p = 0.02

Initial clinical presentations of gastrointestinal bleeding or fatigue, elevated alanine aminotransferase or bilirubin, decreased albumin, positive antinuclear antibody, anti-smooth muscle antibodies, or anti-mitochondrial antibodies M2 subtype are not analyzed due to the small sample size (n < 3)
Ln Natural logarithm, DD Diagnostic delay, WBC White blood cell, HGB Hemoglobin, PLT Platelet, PT Prothrombin time, CT Computed tomography, SD Standard deviation
^a Calculated and tested by Pearson correlation coefficient
^b Initial clinical presentations

ISSN: 1471-230X