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Table 5 Diagnostic characteristics of cytology-based and FFPE-based FISH

From: An assessment of chromosomal alterations detected by fluorescence in situ hybridisation in pancreatobiliary tract malignancy

Characteristics

Cytology-based FISH

paraffin-embedded specimens FISH

Sensitivity

77.8%(28/36)

80.6%(29/36)

Specificity

90.0%(9/10)

90.0%(9/10)

PPV

96.6%(28/29)

96.7%(29/30)

NPV

52.9%(9/17)

56.3%(9/16)

AUC(95%CI)

0.839 (0.702–0.976)

0.853 (0.719–0.987)

  1. P = 1.000 represents comparison between Cytology-based FISH and paraffin-embedded specimens FISH