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Table 2 Compare diagnostic values of Cytology, FISH and FISH & cytology

From: An assessment of chromosomal alterations detected by fluorescence in situ hybridisation in pancreatobiliary tract malignancy

Pathology result

Cytology

FISH

FISH &cytology

Postitive

Negative

Postitive

Negative

Postitive

Negative

Positive (n = 52)

21

31

40

12

41

11

Negative (n = 14)

0

14

1

13

1

13

Total (n = 66)

21

45

41

25

42

24

  1. Any of FISH or cytology positive was regarded as positive of “FISH & cytology”
  2. Cytology Sensitivity = cytology positive/pathology positive = 21/52(40.4%)
  3. Cytology Specificity = cytology negative/ pathology negative = 14/14(100%)
  4. FISH Sensitivity = FISH positive/pathology positive = 40/52(76.9%)
  5. FISH Specificity = FISH negative/ pathology negative = 13/14(92.9%)
  6. FISH &cytology Sensitivity = FISH &cytology positive/pathology positive = 41/52(78.8%)
  7. FISH &cytology Specificity = FISH &cytology negative/pathology negative = 13/14(92.9%)
  8. FISH & cytology FISH combined cytology