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Table 2 Cox regression analysis for variables associated with 90-day mortality in patients with HBV-ACLF

From: A novel predictive model based on inflammatory markers to assess the prognosis of patients with HBV-related acute-on-chronic liver failure: a retrospective cohort study

Variables

Univariate analysis

Multivariate analysis

HR

95%(CI)

P value

Beta coefficient

HR

95%(CI)

P value

TBIL (μmol/L)

1.005

(1.004–1.005)

< 0.001

0.003

1.002

(1.001–1.003)

< 0.001

Cr (μmol/L)

1.008

(1.005–1.010)

< 0.001

0.003

1.003

(1.001–1.005)

0.001

Cyst-c (mg/L)

1.055

(1.014–1.097)

0.008

   

Serum Na+(mmol/L)

0.981

(0.959–1.004)

0.112

   

INR

1.488

(1.342–1.651)

< 0.001

0.317

1.318

(1.163–1.494)

< 0.001

PTA (%)

0.973

(0.959–0.988)

< 0.001

   

WBC (109/L)

1.068

(1.043–1.094)

< 0.001

   

Neutrophils (109/L)

1.082

(1.055–1.110)

< 0.001

   

Monocytes(109/L)

1.080

(0.997–1.170)

0.060

   

Lymphocytes(109/L)

0.856

(0.640–1.144)

0.293

   

RDW (%)

1.112

(1.075–1.15)

< 0.001

0.053

1.047

(1.009–1.086)

0.015

NLR

1.053

(1.038–1.068)

< 0.001

0.027

1.027

(1.009–1.046)

0.003

MLR

1.057

(1.007–1.109)

0.025

   

PLR

1.003

(1.001–1.005)

0.001

   

RLR

1.016

(1.007–1.026)

0.001

   

HE

1.221

    
 

(1.101–1.353)

< 0.001

   

Bacterial infection

0.55

    
 

(0.383–0.785)

0.001

   
  1. TBIL total bilirubin, ALB albumin, Cr creatinine, Cyst-c Cystatin c, Serum Na+ serum sodium, PT prothrombin time, INR international normalized ratio, PTA prothrombin activity, WBC white blood cell count, RDW red blood cell distribution width, NLR neutrophil/lymphocyte ratio, MLR monocyte/lymphocyte ratio, PLR platelet/lymphocyte ratio, RLR RDW/lymphocyte ratio, HE Hepatic encephalopathy, HBV-ACLF hepatitis B virus related acute-on-chronic liver failure
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BMC Gastroenterology

ISSN: 1471-230X

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