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Table 3 Association between RE and H. pylori status pattern and the progression to LSBE adjusted by time-dependent covariate

From: Relationship between time-varying status of reflux esophagitis and Helicobacter pylori and progression to long-segment Barrett’s esophagus: time-dependent Cox proportional-hazards analysis

 

HR*

95% CI

P-value

RE and H. pylori status pattern

 RE(−) /H. pylori (+)

1.00

Reference

 RE(−) /H. pylori (−)

2.45

0.86

7.00

0.09

 RE(+) /H. pylori (+)

4.57

1.26

16.63

0.02

 RE(+) /H. pylori (−)

7.17

2.48

20.73

< 0.001

Male

1.18

0.41

3.45

0.76

Age (year)

1.05

1.01

1.09

0.01

Smoking (100 pack-year)

3.66

1.09

12.29

0.04

Hiatal hernia

3.13

1.49

6.58

0.003

PPI or H2RA

3.99

1.54

10.33

0.004

  1. *Adjusted by time-dependent covariate (RE and H. pylori status pattern, age, smoking, and PPI or H2RA) and baseline time-fixed covariate (male and hiatal hernia)
  2. RE Reflux esophagitis; H. pylori Helicobacter pylori; LSBE Long-segment Barrett’s esophagus; HR Hazard ratio; CI Confidence interval; PPI Proton pump inhibitor; H2RA Histamine H2-receptor antagonist
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BMC Gastroenterology

ISSN: 1471-230X

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