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Table 4 Comparison of corresponding variables of CCT and ROTEM analysis. Agreement is indicated by Cohen’s kappa κ with corresponding p-value

From: Rotational thrombelastometry (ROTEM) improves hemostasis assessment compared to conventional coagulation test in ACLF and Non-ACLF patients

A

 

Non-ACLF

n = 55

ACLF

n = 22

CT EXTEM

<80s

96.4%

81.8%

> 80s

3.6%

18.2%

PT (Quick)

> 50%

80%

45.5%

< 50%

20%

54.6%

 

Non-ACLF

n = 55

ACLF

n = 22

CT EXTEM

 

<80s

>80s

<80s

>80s

PT (Quick)

> 50%

97.7% (43/44)

2.3% (1/44)

100% (10/10)

0.0% (0/10)

< 50%

90.9% (10/11)

9.1% (1/11)

66.7% (1/12)

33.3% (4/12)

κ / p

0.098 / 0.28

0.313 / 0.04

B

 

Non-ACLF

n = 55

ACLF

n = 22

CT INTEM

< 240 s

90.7%

81%

> 240 s

9.3%

19%

aPTT

< 36 s

98.1%

66.7%

> 36 s

1.9%

33.3%

 

Non-ACLF

n = 55

ACLF

n = 22

CT INTEM

 

< 240 s

> 240 s

< 240 s

> 240 s

aPTT

< 36 s

92.5% (50/54)

7.5% (4/54)

100% (14/14)

0.0% (0/14)

> 36 s

0.0% (0/1)

100% (1/1)

42.9% (3/7)

57.1% (4/7)

κ / p

0.31 / 0.02

0.64 / 0.002

C

 

Non-ACLF

n = 55

ACLF

n = 22

MCF EXTEM

> 40 mm

94.5%

81.8%

< 40 mm

5.5%

18.2%

Platelets

> 50/nl

92.7%

68.2%

< 50/nl

7.3%

31.8%

 

Non-ACLF

n = 55

ACLF

n = 22

MCF EXTEM

 

> 40 mm

< 40 mm

> 40 mm

< 40 mm

Platelets

> 50/nl

96.1% (50/52)

3.9% (2/52)

86.7% (13/15)

13.3% (2/15)

< 50/nl

75% (3/4)

25% (1/4)

42.9% (3/7)

57.1% (4/7)

κ / p

0.24 / 0.07

0.46 / 0.03

D

 

Non-ACLF

n = 55

ACLF

n = 22

MCF FIBTEM

> 9 mm

94.5%

68.2%

< 9 mm

5.5%

31.8%

Fibrinogen

> 1.6 g

89.1%

50%

< 1.6 g

10.9%

50%

 

Non-ACLF

n = 55

ACLF

n = 22

MCF FIBTEM

 

> 9 mm

< 9 mm

> 9 mm

< 9 mm

Fibrinogen

> 1.6 g

95.9% (48/50)

4.1% (2/50)

90.9% (10/11)

9.1% (1/11)

< 1.6 g

83.3% (5/6)

16.7% (1/6)

45.5% (5/11)

54.5% (6/11)

 

κ / p

0.16 / 0.20

0.46 / 0.02

  1. ACLF acute-on-chronic liver failure, aPTT activated partial thromboplastin time, CT clotting time; MCF. maximum clot firmness