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Table 3 ROTEM analysis of study population. Median (IQR) is shown with p-values for the group differences based on Mann-Whitney U test

From: Rotational thrombelastometry (ROTEM) improves hemostasis assessment compared to conventional coagulation test in ACLF and Non-ACLF patients

 

Limits of normala

Non-ACLF

n = 55

% outside the limits of normal

ACLF

n = 22

% outside the limits of normal

p-value

NATEM

 CT

254–837 s

549.0 (185.0)

3.7%

650.0 (237.5)

19%

0.01

 CFT

72–357 s

182.0 (124.0)

5.6%

224.0 (114.4)

9.5%

0.42

 MCF

46–69 mm

49.0 (16.0)

25.9%

43.0 (16.5)

38.1%

0.17

 A10

40.0 (16.5)

34.0 (14.5)

0.23

 α-angle

39–75°

57.0 (14.5)

5.7%

53.0 (10.5)

0%

0.40

INTEM

 CT

100–240 s

185.0 (32.0)

9.1%

209.0 (57.0)

19%

0.01

 CFT

30–110 s

112.0 (76.0)

47.3

166.0 (112.5)

76.2%

0.04

 MCF

50–72 mm

52.0 (16.0)

7.3%

44.0 (16.5)

33.3%

0.048

 A10

44–66 s

45.0 (14.0)

43.6%

36.0 (13.5)

76.2%

0.03

 α-angle

70–83°

71.0 (8.0)

41.8%

65.0 (12.0)

61.9%

0.04

EXTEM

 CT

38–79 s

61.0 (11.0)

3.6%

72.0 (17.25)

22.7%

< 0.0001

 CFT

34–159 s

103.0 (63.0)

23.6%

173.5 (126.5)

63.6%

0.008

 MCF

50–72 mm

54.0 (15.0)

5.5%

42.5 (14.3)

27.3%

0.005

 A10

43–65 s

47.0 (17.0)

29.1%

35.5 (14.0)

77.3%

0.004

 α-angle

63–83°

74.0 (10.0)

10.9%

65.0 (15.5)

40.1%

0.001

FIBTEM

 MCF

9–25 mm

16.0 (8.5)

5.5%

13.0 (9.3)

31.8%

< 0.0001

 A10

7–23 s

15.0 (7.0)

1.8%

11.5 (9.8)

13.6%

< 0.0001

 α-angle

75.0 (9.0)

70.5 (14.5)

0.07

APTEM

 CT

35–80 s

62.0 (10.0)

7.3%

64.5 (18.0)

18.2%

0.08

 CFT

35–160 s

99.0 (106.0)

29.1%

181.5 (98.3)

59.1%

0.02

 MCF

53–72 mm

55.0 (15.0)

3.6%

43.5 (15.8)

27.3%

0.005

 A10

48.0 (16.0)

35.0 (13.3)

0.007

 α-angle

74.0 (12.0)

63.5 (19.5)

0.002

  1. A10 amplitudes at 10 min, ACLF acute-on-chronic liver failure, CFT clot formation time, CT clotting time, IQR interquartile range, MCF maximum clot firmness, ML maximal lysis
  2. aby the manufacturer