Table 2 Univariate and multivariate analysis of overall survival
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Age (≥ 70 vs < 70) | 2.023 (0.955–4.287) | 0.066 | ||
Sex (female vs male) | 1.195 (0.544–2.624) | 0.658 | ||
BMI (< 25 vs ≥ 25) | 1.977 (0.754–5.183) | 0.166 | ||
Comorbidities | ||||
Myocardial infarction | 3.510 (1.057–11.655) | 0.040 | 1.825 (0.520–6.413) | 0.348 |
Congestive heart failure | 2.848 (0.990–8.194) | 0.052 | ||
Cerebrovascular accident | 1.330 (0.316–5.603) | 0.697 | ||
COPD | 1.393 (0.331–5.858) | 0.651 | ||
Liver disease | 4.267 (1.291–14.108) | 0.017 | 3.514 (0.868–14.235) | 0.078 |
Chronic kidney disease | 6.615 (0.863–50.679) | 0.069 | ||
Diabetes mellitus | 1.460 (0.647–3.297) | 0.363 | ||
Stage | ||||
(II vs I) | 2.766 (1.003–7.629) | 0.049 | 1.211 (0.314–4.671) | 0.781 |
(III vs I) | 8.214 (3.437–19.631) | < 0.001 | 3.042 (0.784–11.812) | 0.108 |
Tumor size (≥ 50 vs < 50) | 3.210 (1.543–6.678) | 0.002 | 1.080 (0.441–2.648) | 0.866 |
Lymphatic vessel infiltration | 5.739 (2.335–14.104) | < 0.001 | 3.054 (0.879–10.612) | 0.079 |
Histologic type (Intestinal vs Diffuse) | 1.089 (0.52–2.280) | 0.821 | ||
Lymph node dissection | ||||
(D1+ vs D1) | 3.760 (0.854–16.550) | 0.080 | ||
(D2 vs D1) | 3.262 (0.736–14.459) | 0.120 | ||
Complication (CD ≥ 3) | 1.659 (0.394–6.982) | 0.490 | ||
Complication (infection) | 2.343 (0.815–6.739) | 0.114 | ||
CEA (≥ 5.5 vs < 5.5) | 2.306 (0.939–5.665) | 0.068 | ||
CA19–9 (≥ 37 vs < 37) | 2.825 (1.150–6.938) | 0.024 | 1.340 (0.453–3.961) | 0.597 |
mGPS (0 vs 1,2) | 2.519 (0.343–18.517) | 0.364 | ||
NLR (≥ 2.5 vs < 2.5) | 1.182 (0.55–2.542) | 0.669 | ||
PNI (< 45 vs ≥ 45) | 4.261 (1.734–10.47) | 0.002 | 2.889 (1.104–7.563) | 0.031 |