Table 2 Univariate and multivariate analyses of risk factors of postoperative pancreatic fistula after pancreatectomy
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
Non-POPF (n = 94) | POPF (n = 42) | p Value | Hazard ratio | 95% CI | p Value | |
Age ≥ 75 years | 35 (37%) | 12 (29%) | 0.339 | |||
Male | 60 (64%) | 34 (81%) | 0.048 | 1.195 | 0.286–4.990 | 0.807 |
BMI ≥ 25 kg/m2 | 14 (15%) | 11 (26%) | 0.150 | |||
Diabetes mellitus | 22 (23%) | 5 (12%) | 0.163 | |||
Habitual smoking | 43 (45%) | 28 (67%) | 0.027 | 2.571 | 0.938–7.051 | 0.067 |
Habitual alcohol consumption | 37 (39%) | 22 (52%) | 0.193 | |||
Preoperative biliary drainage | 34 (36%) | 12 (29%) | 0.437 | |||
T-Bil ≥ 1 mg/dL | 67 (71%) | 28 (67%) | 0.686 | |||
Alb ≥3.5 mg/dL | 66 (70%) | 34 (81%) | 0.290 | |||
CRP ≥ 1 mg/dL | 19 (20%) | 9 (21%) | 1.000 | |||
PNI < 45 | 51 (54%) | 31 (74%) | 0.037 | 2.659 | 1.045–6.767 | 0.040 |
Sarcopenia | 40 (43%) | 13 (31%) | 0.254 | |||
VATA ≥ 90 cm2/m2 | 39 (41%) | 32 (76%) | 0.0002 | |||
SATA ≥88 cm2/m2 | 55 (59%) | 28 (67%) | 0.448 | |||
SMI < 42 cm2/m2 | 36 (38%) | 10 (24%) | 0.099 | |||
VATA/SATA ≥ 0.9 | 45 (48%) | 32 (76%) | 0.003 | 0.712 | 0.180–2.809 | 0.627 |
VATA/SMI ≥ 1.4 | 52 (55%) | 39 (93%) | 0.0004 | 14.712 | 3.064–70.650 | 0.001 |
FRS high score (> 4 score) | 36 (38%) | 30 (71%) | 0.006 | 4.820 | 1.960–11.855 | 0.001 |
Pancreatic adenocarcinoma or pancreatitis | 45 (48%) | 24 (57%) | 0.357 | |||
Soft pancreatic texture | 42 (45%) | 30 (71%) | 0.005 | |||
Pancreatic duct size < 3 mm | 33 (35%) | 28 (67%) | 0.0011 | |||
Estimated blood loss > 701 mL | 47 (50%) | 22 (52%) | 0.849 |