From: Hepatocellular carcinoma in adult thalassemia patients: an expert opinion based on current evidence
Stage | Very Early Stage 0 | Early Stage A | Intermediate Stage B | Advanced Stage C | Terminal Stage D |
---|---|---|---|---|---|
Liver Function | + | + | + | + | – |
Performance Status | ECOG-PS 0 | ECOG-PS 0 | ECOG-PS 0 | ECOG-PS 1–2 | ECOG-PS 1–2 |
Tumor Burden | Solitary nodule ≤ 2 cm | Solitary nodule ≤ 2 cm . 2–3 nodules all < 3 cm | Multinodular (> 3 nodules, or ≥ 2 nodules if any > 3 cm) | Macrovascular invasion or extraepatic spread | Non-transplantable HCC |