Changes in inflammatory cytokines, antioxidants and liver stiffness after chelation therapy in individuals with chronic lead poisoning

Table 2 Potential factors that may be associated with liver fibrosis and steatosis in the initial cross-sectional cohort

Parameters	Factors associated with liver fibrosis				Factors associated with liver steatosis
	Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
	Pearson Correlation	P-value	Pearson Correlation	P-value	Pearson Correlation	P-value	Pearson Correlation	P-value
Age	0.215	0.047	0.195	0.060	- 0.042	0.703	–	–
Sex	- 0.155	0.153	–	–	-0.237	0.028	-0.161	0.062
BLL	-0.086	0.430	–	–	-0.075	0.493	–	–
Duration of lead exposure	0.249	0.021	0.229	0.026	0.020	0.854	–	–
Waist circumference	0.220	0.076	–	–	0.702	< 0.001	0.524	< 0.001
BMI	0.226	0.037	0.107	0.350	0.660	< 0.001	2.064	0.360
Liver steatosis	0.242	0.025	0.080	0.525	1	–	–	–
Liver fibrosis	1	–	–	–	0.242	0.025	2.155	0.656
SGOT	0.161	0.142	–	–	0.329	0.002	−0.531	0.273
SGPT	0.332	0.002	0.317	0.002	0.566	< 0.001	0.397	0.018
ALP	0.222	0.041	0.107	0.347	0.154	0.161	–	–

Abbreviations: BLL blood lead level, BMI body mass index, SGOT serum glutamate oxaloacetate transaminase, SGPT serum glutamate pyruvate aminotransferase, ALP alkaline phosphatase

ISSN: 1471-230X