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Table 2 Potential factors that may be associated with liver fibrosis and steatosis in the initial cross-sectional cohort

From: Changes in inflammatory cytokines, antioxidants and liver stiffness after chelation therapy in individuals with chronic lead poisoning

Parameters Factors associated with liver fibrosis Factors associated with liver steatosis
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
Pearson Correlation P-value Pearson Correlation P-value Pearson Correlation P-value Pearson Correlation P-value
Age 0.215 0.047 0.195 0.060 - 0.042 0.703 – –
Sex - 0.155 0.153 – – -0.237 0.028 -0.161 0.062
BLL -0.086 0.430 – – -0.075 0.493 – –
Duration of lead exposure 0.249 0.021 0.229 0.026 0.020 0.854 – –
Waist circumference 0.220 0.076 – – 0.702 < 0.001 0.524 < 0.001
BMI 0.226 0.037 0.107 0.350 0.660 < 0.001 2.064 0.360
Liver steatosis 0.242 0.025 0.080 0.525 1 – – –
Liver fibrosis 1 – – – 0.242 0.025 2.155 0.656
SGOT 0.161 0.142 – – 0.329 0.002 −0.531 0.273
SGPT 0.332 0.002 0.317 0.002 0.566 < 0.001 0.397 0.018
ALP 0.222 0.041 0.107 0.347 0.154 0.161 – –
  1. Abbreviations: BLL blood lead level, BMI body mass index, SGOT serum glutamate oxaloacetate transaminase, SGPT serum glutamate pyruvate aminotransferase, ALP alkaline phosphatase
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BMC Gastroenterology

ISSN: 1471-230X

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