Fig. 3
From: Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis
Regulation of disease-associated candidate genes in NASH patients and GAN DIO-NASH mice. a Disease-associated hepatic candidate genes, b Selected hepatic genes representing various drug targets for NASH. Color gradients indicate significantly upregulated (red color) and downregulated (blue color) gene expression in NASH patients (n = 16) and GAN DIO-NASH mice (n = 25) compared to corresponding control group (healthy normal-weight human individuals, n = 14; chow-fed mice, n = 10). Candidate genes are listed in Table S1